Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
| ▸ | ECE1 | P42892 | 7/20 | 0.42 |
| ▸ | F10 | P00742 | 4/20 | 0.41 |
| ▸ | CCR2 | P41597 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL831780 | 0.99 | MAOB (0.47) | MAOBECE1F10CCR2IDO1 | |
| SCHEMBL833415 | 0.84 | MAOB (0.45) | MAOBECE1F10CCR2PTGDR2 | |
| SCHEMBL832764 | 0.83 | ECE1 (0.46) | MAOBECE1F10CCR2PTGDR2 | |
| SCHEMBL832765 | 0.83 | ECE1 (0.44) | MAOBECE1F10CCR2TP53 | |
| SCHEMBL3153257 | 0.82 | MAOB (0.53) | MAOBECE1F10CCR2IDO1 | |
| SCHEMBL3153688 | 0.82 | MAOB (0.53) | MAOBECE1F10IDO1 | |
| SCHEMBL3148861 | 0.82 | MAOB (0.50) | MAOBECE1F10CCR2PTGDR2 | |
| SCHEMBL3150006 | 0.80 | MAOB (0.49) | MAOBECE1F10CCR2MAPT | |
| SCHEMBL3158981 | 0.79 | ECE1 (0.47) | MAOBECE1F10CCR2TP53 | |
| SCHEMBL3158017 | 0.78 | MAOB (0.47) | MAOBECE1F10CCR2PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1987010-B1 | TRICYCLIC N-HETEROARYL-CARBOXAMIDE DERIVATIVES CONTAINING A BENZIMIDAZOLE UNIT, METHOD FOR PREPARING SAME AND THEIR THERAPEUTIC USE | SANOFI AVENTIS (FR) | 2010-04-07 | — | — | EP | disclosed |