Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 4/20 | 0.43 |
| ▸ | FGFR2 | P21802 | 4/20 | 0.43 |
| ▸ | FGFR3 | P22607 | 4/20 | 0.43 |
| ▸ | FGFR4 | P22455 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.37 |
| ▸ | ITK | Q08881 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.36 |
| ▸ | EGFR | P00533 | 6/20 | 0.35 |
| ▸ | BTK | Q06187 | 2/20 | 0.35 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
| ▸ | YES1 | P07947 | 1/20 | 0.35 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.35 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.35 |
| ▸ | VCP | P55072 | 1/20 | 0.35 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31264711 | 0.98 | FGFR1 (0.43) | FGFR1FGFR2FGFR3FGFR4CYP3A4 | |
| SCHEMBL31264658 | 0.97 | FGFR1 (0.42) | FGFR1FGFR2FGFR3FGFR4CYP3A4 | |
| SCHEMBL31264731 | 0.89 | FGFR1 (0.41) | FGFR1FGFR2FGFR3FGFR4CYP3A4 | |
| SCHEMBL31264636 | 0.88 | FGFR1 (0.40) | FGFR1FGFR2FGFR3FGFR4CYP3A4 | |
| SCHEMBL31264664 | 0.81 | EIF2AK3 (0.50) | — | |
| SCHEMBL31264760 | 0.80 | EIF2AK3 (0.50) | — | |
| SCHEMBL31264739 | 0.79 | EIF2AK3 (0.49) | — | |
| SCHEMBL31264661 | 0.78 | FGFR1 (0.58) | FGFR1FGFR2FGFR3FGFR4CYP3A4 | |
| SCHEMBL25129489 | 0.76 | BTK (0.43) | PIK3CDEGFRBTKRPS6KB1FYN | |
| SCHEMBL29407696 | 0.76 | BTK (0.43) | PIK3CDEGFRBTKRPS6KB1FYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4722216-A1 | PYRROLOPYRIMIDINE DERIVATIVE AND USE THEREOF IN MEDICINE | Kangbaida (Sichuan) Biotechnology Co., Ltd. (CN) | 2026-04-08 | — | — | EP | disclosed |
| CN-119894900-A | Pyrrolo pyrimidine derivative and application thereof in medicine | 康百达（四川）生物医药科技有限公司 | 2025-04-25 | — | — | CN | disclosed |
| WO-2024251147-A1 | PYRROLOPYRIMIDINE DERIVATIVE AND USE THEREOF IN MEDICINE | 康百达（四川）生物医药科技有限公司 | 2024-12-12 | — | — | WO | disclosed |