Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 13/20 | 0.57 |
| ▸ | TNF | P01375 | 9/20 | 0.54 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22264678 | 1.00 | PDE4D (0.57) | PDE4DTNFLRRK2 | |
| SCHEMBL20839527 | 1.00 | PDE4D (0.57) | PDE4DTNFLRRK2 | |
| SCHEMBL20838994 | 0.89 | PDE4D (0.63) | PDE4DTNF | |
| SCHEMBL22264695 | 0.88 | PDE4D (0.72) | PDE4DTNF | |
| SCHEMBL22264687 | 0.88 | PDE4D (0.73) | PDE4DTNF | |
| SCHEMBL29735388 | 0.88 | PDE4D (0.73) | PDE4DTNF | |
| SCHEMBL22264617 | 0.88 | PDE4D (0.73) | PDE4DTNF | |
| SCHEMBL22264648 | 0.88 | PDE4D (0.73) | PDE4DTNF | |
| SCHEMBL29735350 | 0.88 | PDE4D (0.73) | PDE4DTNF | |
| SCHEMBL22272364 | 0.86 | TNF (0.73) | PDE4DTNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3684775-B1 | SUBSTITUTED DIHYDROTHIENOPYRIMIDINES AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS | UNION THERAPEUTICS AS (DK) | 2024-11-20 | — | — | EP | claimed |