SCHEMBL312671

SCHEMBL312671

O=S(=O)(O)CCCCOCCCCS(=O)(=O)O.[NaH]

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 1/20 0.46
LMNA P02545 4/20 0.38
BLM P54132 2/20 0.38
PTGS1 P23219 1/20 0.38
PDE4A P27815 1/20 0.38
SLC6A6 P31641 1/20 0.38
CYP2C19 P33261 1/20 0.38
ALDH1A1 P00352 3/20 0.32
POLB P06746 2/20 0.32
RAB9A P51151 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
ALOX15 P16050 2/20 0.32
KDM4E B2RXH2 2/20 0.32
MAPT P10636 2/20 0.32
HTT P42858 2/20 0.32
NPC1 O15118 1/20 0.32
BRCA1 P38398 1/20 0.32
GMNN O75496 1/20 0.32
PKM P14618 1/20 0.32
THPO P40225 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL193290 1.00 APP (0.46) APPLMNABLMPTGS1PDE4A
SCHEMBL37545 0.97 APP (0.48) APPLMNABLMPTGS1PDE4A
SCHEMBL30782568 0.95 APP (0.46) APPLMNABLMPTGS1PDE4A
SCHEMBL30133577 0.95 APP (0.46) APPLMNABLMPTGS1PDE4A
SCHEMBL420986 0.95 APP (0.46) APPLMNABLMPTGS1PDE4A
Bromide SCHEMBL31659017 0.95 APP (0.46) APPLMNABLMPTGS1PDE4A
SCHEMBL419968 0.95 APP (0.46) APPLMNABLMPTGS1PDE4A
SCHEMBL754172 0.95 APP (0.46) APPLMNABLMPTGS1PDE4A
SCHEMBL18380848 0.95 APP (0.46) APPLMNABLMPTGS1PDE4A
SCHEMBL754168 0.95 APP (0.46) APPLMNABLMPTGS1PDE4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 191 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4633609-A1 LIPID NANOPARTICLES LYOPHILIZATION METHODS AND COMPOSITIONS Global Life Sciences Solutions Canada ULC (CA) 2025-10-22 EP claimed
WO-2024126423-A1 LIPID NANOPARTICLES LYOPHILIZATION METHODS AND COMPOSITIONS Precision NanoSystems ULC (CA) 2024-06-20 WO claimed
CN-117982682-A Compositions comprising an RNA polymerase inhibitor and a cyclodextrin for treating viral infections 吉利德科学公司 2024-05-07 CN claimed
CN-111093627-B Compositions comprising an RNA polymerase inhibitor and a cyclodextrin for treating viral infections 吉利德科学公司 2024-03-08 CN claimed
WO-2023108156-A1 ZIPRASIDONE FORMULATIONS BELOTECA, INC. (US) 2023-06-15 WO claimed
CN-115835885-A Preparation of pharmaceutical composition comprising odaterol and budesonide 广州谷森制药有限公司 2023-03-21 CN claimed
EP-4132651-A1 INHALATION FORMULATIONS OF 1'-CYANO SUBSTITUTED CARBANUCLEOSIDE ANALOGS GILEAD SCIENCES, INC. (US) 2023-02-15 EP claimed
CN-115362004-A Inhalation formulations of 1' -cyano-substituted carbon nucleoside analogs 吉利德科学公司 2022-11-18 CN claimed
US-20220249395-A1 PHARMACEUTICAL FORMULATIONS FOR A LIQUID DOSAGE FORM AND A CONTROLLED RELEASE DOSAGE FORM INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2022-08-11 US claimed
CN-112494444-A Hydrophilic gel sustained-release tablet containing echinacoside and preparation method and application thereof 建昌帮药业有限公司 2021-03-16 CN claimed
EP-1819350-A2 PHARMACEUTICAL FORMULATIONS CYTIDINE ANALOGS AND DERIVATIVES SuperGen, Inc. (US) 2007-08-22 EP claimed
EP-1819227-A1 PHARMACEUTICAL FORMULATION OF DECITABINE SuperGen, Inc. (US) 2007-08-22 EP claimed
WO-2006071491-A1 PHARMACEUTICAL FORMULATION OF DECITABINE SUPERGEN, INC. (US) 2006-07-06 WO claimed
US-20060128653-A1 Pharmaceutical formulation of decitabine SUPERGEN, INC. 2006-06-15 US claimed
WO-2006063111-A2 PHARMACEUTICAL FORMULATIONS CYTIDINE ANALOGS AND DERIVATIVES SUPERGEN, INC. (US) 2006-06-15 WO claimed
US-20060128654-A1 Pharmaceutical formulation of cytidine analogs and derivatives SUPERGEN, INC. 2006-06-15 US claimed
US-20040053888-A1 Cyclodextrin-containing pharmaceutical preparation DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2004-03-18 US claimed
EP-1348432-A1 CYCLODEXTRIN-CONTAINING PHARMACEUTICAL PREPARATION DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2003-10-01 EP claimed
US-6596706-B1 For the treatment of circulatory diseases cerebral diseases DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2003-07-22 US claimed
EP-1029872-A1 PIPERAZINE-CYCLODEXTRIN COMPLEXES DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2000-08-23 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040053888-A1 Cyclodextrin-containing pharmaceutical preparation SLCO2B1, RPS27L, SEC23IP APP 2181/4885LMNA 4571/4885BLM 3702/4885
US-20220249395-A1 PHARMACEUTICAL FORMULATIONS FOR A LIQUID DOSAGE FORM AND A CONTROLLED RELEASE DOSAGE FORM HRH4, HRH3, NR4A3 APP 828/4885LMNA 3657/4885BLM 2819/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.