Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 3/20 | 0.51 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.51 |
| ▸ | TNFSF11 | O14788 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 3/20 | 0.40 |
| ▸ | KRAS | P01116 | 1/20 | 0.40 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | FBP1 | P09467 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26604365 | 1.00 | PDE4A (0.51) | PDE4APDE4DTNFSF11KMT2ASMN1; SMN2 | |
| SCHEMBL372023 | 0.88 | PDE4A (0.62) | PDE4APDE4DKMT2ASMN1; SMN2PDE3B | |
| SCHEMBL28486664 | 0.84 | PDE4A (0.47) | PDE4APDE4DTNFSF11KMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL29127441 | 0.83 | PDE4A (0.46) | PDE4APDE4DTNFSF11KMT2ASMN1; SMN2 | |
| SCHEMBL24792134 | 0.79 | PDE4A (0.51) | PDE4APDE4DPDE3BPDE3AEGFR | |
| SCHEMBL30014476 | 0.79 | PDE4A (0.51) | PDE4APDE4DPDE3BPDE3AEGFR | |
| SCHEMBL27118706 | 0.79 | PDE4A (0.51) | PDE4APDE4DPDE3BPDE3AEGFR | |
| SCHEMBL217338 | 0.78 | PDE10A (0.52) | TNFSF11EGFRKDR | |
| Hydrochloric Acid SCHEMBL28016254 | 0.77 | PDE10A (0.51) | TNFSF11EGFRKDR | |
| SCHEMBL24791028 | 0.76 | PDE4A (0.49) | PDE4APDE4DKMT2APDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119095849-A | Macrocyclic heterocycles and uses thereof | 金橘生物科技公司 | 2024-12-06 | — | — | CN | disclosed |