Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.37 |
| ▸ | USP2 | O75604 | 9/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 9/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 9/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 9/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 9/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CCR2 | P41597 | 1/20 | 0.34 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 5/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31269322 | 1.00 | PPARG (0.37) | PPARGUSP2CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL30983500 | 0.93 | CNR1 (0.35) | PPARGLMNAMEN1KMT2ATLR7 | |
| SCHEMBL30983374 | 0.93 | CNR1 (0.35) | PPARGLMNAMEN1KMT2ATLR7 | |
| SCHEMBL30983474 | 0.93 | CNR1 (0.35) | PPARGLMNAMEN1KMT2ATLR7 | |
| SCHEMBL31269301 | 0.92 | S1PR1 (0.35) | CYP1A2CYP3A4CYP2C9CYP2C19MAPK1 | |
| SCHEMBL31269306 | 0.92 | PIK3CD (0.32) | PPARGKMT2APIK3CD | |
| SCHEMBL31269103 | 0.92 | ALOX5AP (0.33) | KMT2APIK3CD | |
| SCHEMBL31268741 | 0.92 | PIK3CD (0.32) | PPARGPIK3CD | |
| SCHEMBL31268989 | 0.91 | S1PR1 (0.40) | PPARGALDH1A1LMNAKMT2AHTR6 | |
| SCHEMBL31268822 | 0.91 | SCN1A (0.35) | KMT2ATLR7PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4689155-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | Astrazeneca AB (SE) | 2026-02-11 | — | — | EP | disclosed |
| WO-2024201368-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | ASTRAZENECA AB (SE) | 2024-10-03 | — | — | WO | disclosed |