Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 16/20 | 0.38 |
| ▸ | CBLB | Q13191 | 2/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31268735 | 0.91 | PIK3CD (0.39) | PIK3CDKDM1APIK3R1 | |
| SCHEMBL31269279 | 0.91 | PIK3CD (0.39) | PIK3CD | |
| SCHEMBL31269415 | 0.89 | PIK3CD (0.40) | PIK3CDCBLB | |
| SCHEMBL31268858 | 0.89 | PIK3CD (0.43) | PIK3CDPIK3R1 | |
| SCHEMBL31269121 | 0.89 | PIK3CD (0.40) | PIK3CDLRRK2 | |
| SCHEMBL31268886 | 0.89 | PIK3CD (0.40) | PIK3CD | |
| SCHEMBL31268957 | 0.89 | PIK3CD (0.40) | PIK3CDKDM1A | |
| SCHEMBL31269085 | 0.88 | PIK3CD (0.37) | PIK3CD | |
| SCHEMBL31268972 | 0.88 | PIK3CD (0.38) | PIK3CD | |
| SCHEMBL31269241 | 0.88 | PIK3CD (0.38) | PIK3CDLRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4689155-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | Astrazeneca AB (SE) | 2026-02-11 | — | — | EP | disclosed |
| WO-2024201368-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | ASTRAZENECA AB (SE) | 2024-10-03 | — | — | WO | disclosed |