Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 18/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 17/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | KDM4A | O75164 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13521580 | 0.91 | GRIN1 (0.45) | GRIN2BGRIN1HPGDHTTHSD17B10 | |
| SCHEMBL13521717 | 0.87 | GRIN2B (0.49) | GRIN2BGRIN1KDM4EALDH1A1HTT | |
| SCHEMBL3264885 | 0.87 | GRIN2B (0.49) | GRIN2BGRIN1 | |
| SCHEMBL3118279 | 0.86 | GRIN2B (0.42) | GRIN2BGRIN1 | |
| SCHEMBL13521576 | 0.86 | GRIN2B (0.42) | GRIN2BGRIN1KDM4EALDH1A1HPGD | |
| SCHEMBL13521586 | 0.83 | GRIN2B (0.45) | GRIN2BGRIN1 | |
| SCHEMBL3126458 | 0.81 | GRIN2B (0.47) | GRIN2BGRIN1ALDH1A1 | |
| SCHEMBL13521616 | 0.81 | GRIN2B (0.43) | GRIN2BGRIN1KDM4EALDH1A1 | |
| SCHEMBL3122850 | 0.81 | GRIN1 (0.50) | GRIN2BGRIN1L3MBTL1 | |
| SCHEMBL13521587 | 0.81 | GRIN1 (0.43) | GRIN2BGRIN1KDM4EKDM4AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010008777-A2 | FUSED AZABICYCLIC PYRIDINES | LIGAND PHARMACEUTICALS INC. (US) | 2010-01-21 | — | — | WO | claimed |
| WO-2010008777-A2 | FUSED AZABICYCLIC PYRIDINES | LIGAND PHARMACEUTICALS INC. (US) | 2010-01-21 | — | — | WO | disclosed |