Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MGAM | O43451 | 2/20 | 0.45 |
| ▸ | SI | P14410 | 2/20 | 0.45 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31269955 | 1.00 | KDM4E (0.57) | KDM4EL3MBTL1MGAMSIAOC3 | |
| SCHEMBL31270029 | 0.91 | KDM4E (0.62) | KDM4EL3MBTL1MGAMSIAOC3 | |
| SCHEMBL31269950 | 0.91 | KDM4E (0.64) | KDM4EL3MBTL1AOC3ADRB2 | |
| SCHEMBL31270098 | 0.91 | KDM4E (0.64) | KDM4EL3MBTL1AOC3ADRB2 | |
| SCHEMBL31269709 | 0.91 | KDM4E (0.59) | KDM4EL3MBTL1MGAMSIAOC3 | |
| SCHEMBL31270090 | 0.91 | KDM4E (0.59) | KDM4EL3MBTL1MGAMSIAOC3 | |
| SCHEMBL31269747 | 0.85 | KDM4E (0.42) | KDM4EL3MBTL1MEN1KMT2AADRB2 | |
| SCHEMBL31270370 | 0.85 | KDM4E (0.66) | KDM4EL3MBTL1AOC3ADRB2 | |
| Hydrochloric Acid SCHEMBL14126826 | 0.84 | KDM4E (0.71) | KDM4EL3MBTL1MGAMSIAOC3 | |
| SCHEMBL31270005 | 0.84 | ADRB3 (0.48) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4688742-A1 | CYCLOHEXYL OR HETEROCYCLOALKYL BETA-HYDROXY ALKYL AMINES FOR USE IN THE TREATMENT OF HYPERGLYCAEMIA AND DISORDERS CHARACTERISED BY HYPERGLYCAEMIA | Atrogi AB (SE) | 2026-02-11 | — | — | EP | claimed |
| WO-2024200768-A1 | CYCLOHEXYL OR HETEROCYCLOALKYL BETA-HYDROXY ALKYL AMINES FOR USE IN THE TREATMENT OF HYPERGLYCAEMIA AND DISORDERS CHARACTERISED BY HYPERGLYCAEMIA | ATROGI AB (SE) | 2024-10-03 | — | — | WO | claimed |
| EP-4688742-A1 | CYCLOHEXYL OR HETEROCYCLOALKYL BETA-HYDROXY ALKYL AMINES FOR USE IN THE TREATMENT OF HYPERGLYCAEMIA AND DISORDERS CHARACTERISED BY HYPERGLYCAEMIA | Atrogi AB (SE) | 2026-02-11 | — | — | EP | disclosed |
| WO-2024200768-A1 | CYCLOHEXYL OR HETEROCYCLOALKYL BETA-HYDROXY ALKYL AMINES FOR USE IN THE TREATMENT OF HYPERGLYCAEMIA AND DISORDERS CHARACTERISED BY HYPERGLYCAEMIA | ATROGI AB (SE) | 2024-10-03 | — | — | WO | disclosed |