⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25032428 | 1.00 | — | — | |
| SCHEMBL25032432 | 0.81 | — | — | |
| SCHEMBL29212422 | 0.80 | — | — | |
| SCHEMBL31270572 | 0.80 | — | — | |
| SCHEMBL29212260 | 0.78 | PDPK1 (0.31) | — | |
| SCHEMBL31270321 | 0.78 | PDPK1 (0.31) | — | |
| SCHEMBL25032431 | 0.74 | METAP1 (0.37) | — | |
| SCHEMBL30832676 | 0.73 | — | — | |
| SCHEMBL29212469 | 0.73 | — | — | |
| SCHEMBL30871128 | 0.72 | SYK (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240400591-A1 | COMPOUNDS TARGETING MUTANT OF P53 | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2024-12-05 | — | — | US | disclosed |