Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.56 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.56 |
| ▸ | ACACB | O00763 | 1/20 | 0.52 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | NAMPT | P43490 | 3/20 | 0.47 |
| ▸ | EP300 | Q09472 | 2/20 | 0.47 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12682930 | 1.00 | HDAC6 (0.56) | HDAC6HDAC8NOTUMACACBPRMT5 | |
| SCHEMBL17560214 | 0.94 | NOTUM (0.56) | HDAC6HDAC8NOTUMACACBPRMT5 | |
| SCHEMBL1027755 | 0.89 | HDAC6 (0.56) | HDAC6HDAC8ACACBESR1ESR2 | |
| SCHEMBL1263724 | 0.85 | HDAC6 (0.53) | HDAC6HDAC8ACACBESR1ESR2 | |
| SCHEMBL8283285 | 0.85 | ESR2 (0.70) | HDAC6HDAC8ACACBESR1ESR2 | |
| SCHEMBL1027560 | 0.84 | HDAC6 (0.73) | HDAC6HDAC8NOTUMPRMT5HDAC3 | |
| SCHEMBL20178664 | 0.84 | HDAC6 (0.51) | HDAC6HDAC8ACACBESR1ESR2 | |
| SCHEMBL10120405 | 0.84 | HDAC6 (0.52) | HDAC6HDAC8ACACBESR1ESR2 | |
| SCHEMBL17560164 | 0.84 | NOTUM (0.61) | HDAC6HDAC8NOTUMPRMT5ESR1 | |
| SCHEMBL30810841 | 0.83 | HDAC6 (0.51) | HDAC6HDAC8ACACBESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119173512-A | Small molecule inhibitors of ubiquitin-specific protease 1 (USP 1) and uses thereof | 英矽智能科技知识产权有限公司 | 2024-12-20 | — | — | CN | disclosed |