Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | FLT4 | P35916 | 1/20 | 0.30 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31278457 | 0.98 | CYP1A2 (0.47) | CYP1A2CYP2C19PDPK1MAPTMEN1 | |
| SCHEMBL3392861 | 0.73 | CYP1A2 (0.48) | CYP1A2CYP2C19PDPK1MAPTMEN1 | |
| SCHEMBL6935919 | 0.70 | — | — | |
| Ammonia Solution, Strong SCHEMBL4358263 | 0.68 | CYP1A2 (0.44) | CYP1A2CYP2C19PDPK1MAPTMEN1 | |
| SCHEMBL23178892 | 0.68 | CYP1A2 (0.30) | CYP1A2CYP2C19MAPTALDH1A1 | |
| SCHEMBL16431132 | 0.67 | CYP1A2 (0.51) | CYP1A2CYP2C19 | |
| SCHEMBL16431133 | 0.65 | CYP1A2 (1.00) | CYP1A2CYP2C19PDPK1MEN1KMT2A | |
| SCHEMBL6938040 | 0.65 | CYP1A2 (0.42) | CYP1A2CYP2C19PDPK1MAPTALDH1A1 | |
| SCHEMBL6938627 | 0.65 | CYP1A2 (0.42) | CYP1A2CYP2C19PDPK1MAPTALDH1A1 | |
| SCHEMBL6935926 | 0.65 | CYP1A2 (0.42) | CYP1A2CYP2C19PDPK1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4720067-A1 | BICYCLIC HETEROARYLAMIDES HAVING GPR68 MODULATING ACTIVITY | Recursion Pharmaceuticals, Inc. (US) | 2026-04-08 | — | — | EP | disclosed |
| WO-2024246559-A1 | BICYCLIC HETEROARYLAMIDES HAVING GPR68 MODULATING ACTIVITY | EXSCIENTIA AI LIMITED (GB) | 2024-12-05 | — | — | WO | disclosed |