Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 3/20 | 0.56 |
| ▸ | TYK2 | P29597 | 17/20 | 0.50 |
| ▸ | JAK1 | P23458 | 3/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31280374 | 0.92 | JAK2 (0.56) | JAK2TYK2JAK1 | |
| SCHEMBL31280222 | 0.90 | TYK2 (0.56) | JAK2TYK2JAK1CYP2C19 | |
| SCHEMBL24775864 | 0.85 | JAK2 (0.75) | JAK2TYK2JAK1CYP2C19 | |
| SCHEMBL29947332 | 0.85 | JAK2 (0.75) | JAK2TYK2JAK1CYP2C19 | |
| SCHEMBL30079429 | 0.83 | TYK2 (0.62) | JAK2TYK2JAK1 | |
| SCHEMBL24823051 | 0.83 | TYK2 (0.62) | JAK2TYK2JAK1 | |
| SCHEMBL31280405 | 0.81 | JAK2 (0.56) | JAK2TYK2JAK1CYP2C19 | |
| SCHEMBL30079529 | 0.80 | TYK2 (0.76) | JAK2TYK2JAK1 | |
| SCHEMBL30079131 | 0.77 | TYK2 (0.75) | JAK2TYK2JAK1 | |
| SCHEMBL24776106 | 0.76 | JAK2 (0.70) | JAK2TYK2JAK1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4727941-A1 | TYK2 INHIBITORS AND COMPOSITIONS AND METHODS THEREOF | Lynk Pharmaceuticals Co. Ltd. (CN) | 2026-04-22 | — | — | EP | disclosed |
| WO-2024255885-A1 | TYK2 INHIBITORS AND COMPOSITIONS AND METHODS THEREOF | LYNK PHARMACEUTICALS CO. LTD. (CN) | 2024-12-19 | — | — | WO | disclosed |