Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 16/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP3A5 | P20815 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3134372 | 0.90 | HRH3 (0.55) | HRH3POLB | |
| SCHEMBL2852634 | 0.79 | HRH3 (0.78) | HRH3POLBCYP3A4 | |
| SCHEMBL2848734 | 0.79 | HRH3 (0.78) | HRH3POLB | |
| SCHEMBL3141638 | 0.78 | HRH3 (0.52) | HRH3POLB | |
| SCHEMBL2843344 | 0.77 | HRH3 (0.74) | HRH3POLB | |
| SCHEMBL3134332 | 0.76 | HRH3 (0.55) | HRH3POLB | |
| SCHEMBL2848351 | 0.76 | HRH3 (0.60) | HRH3POLB | |
| SCHEMBL2848874 | 0.75 | HRH3 (0.81) | HRH3CYP3A4 | |
| SCHEMBL2844348 | 0.74 | HRH3 (0.79) | HRH3CYP3A4 | |
| SCHEMBL2851223 | 0.72 | HRH3 (0.76) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010062245-A1 | SPIROCYCLOBUTYL PIPERIDINE DERIVATIVES | ASTRAZENECA AB (SE) | 2010-06-03 | — | — | WO | claimed |