Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.45 |
| ▸ | DRD1 | P21728 | 3/20 | 0.44 |
| ▸ | HTR2C | P28335 | 3/20 | 0.44 |
| ▸ | HRH1 | P35367 | 3/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.44 |
| ▸ | HTR2B | P41595 | 3/20 | 0.44 |
| ▸ | DRD2 | P14416 | 2/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.39 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 2/20 | 0.38 |
| ▸ | HRH2 | P25021 | 2/20 | 0.38 |
| ▸ | HTR1D | P28221 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25697970 | 0.92 | KCNH2 (0.42) | PDE2ADRD1HTR2CHRH1ADRA1B | |
| SCHEMBL4610694 | 0.81 | CHRM2 (0.49) | DRD1HTR2CHRH1ADRA1BHTR2B | |
| SCHEMBL4610480 | 0.81 | CHRM2 (0.49) | DRD1HTR2CHRH1ADRA1BHTR2B | |
| SCHEMBL31280766 | 0.81 | SLC6A2 (0.37) | HTR2CHRH1HTR2BHTR2AKCNH2 | |
| SCHEMBL23293136 | 0.79 | KDM4E (0.39) | — | |
| SCHEMBL12993119 | 0.78 | MGAM (0.42) | KCNH2SLC6A4SLC6A2ADRA1A | |
| SCHEMBL1349204 | 0.78 | PDE2A (0.65) | PDE2AHTR2CHTR2ASLC6A4SLC6A2 | |
| SCHEMBL12563119 | 0.78 | MGAM (0.42) | KCNH2SLC6A4SLC6A2ADRA1A | |
| SCHEMBL31280738 | 0.77 | PDE2A (0.45) | PDE2AKCNH2ADRA1A | |
| SCHEMBL21816497 | 0.77 | CYP3A4 (0.46) | ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4727941-A1 | TYK2 INHIBITORS AND COMPOSITIONS AND METHODS THEREOF | Lynk Pharmaceuticals Co. Ltd. (CN) | 2026-04-22 | — | — | EP | disclosed |
| WO-2024255885-A1 | TYK2 INHIBITORS AND COMPOSITIONS AND METHODS THEREOF | LYNK PHARMACEUTICALS CO. LTD. (CN) | 2024-12-19 | — | — | WO | disclosed |