Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP3A5 | P20815 | 2/20 | 0.46 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.45 |
| ▸ | STS | P08842 | 3/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.44 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.42 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31282716 | 1.00 | USP30 (0.58) | USP30CYP3A4CYP3A5MKNK1STS | |
| SCHEMBL26274564 | 1.00 | USP30 (0.58) | USP30CYP3A4CYP3A5MKNK1STS | |
| SCHEMBL31282704 | 1.00 | USP30 (0.58) | USP30CYP3A4CYP3A5MKNK1STS | |
| SCHEMBL31283891 | 0.88 | USP30 (0.47) | USP30STSKMT2AMEN1CNR1 | |
| SCHEMBL31282658 | 0.88 | USP30 (0.47) | USP30STSKMT2AMEN1CNR1 | |
| SCHEMBL25387627 | 0.88 | STS (0.47) | USP30STSKMT2AMEN1CNR1 | |
| SCHEMBL26274175 | 0.88 | USP30 (0.47) | USP30STSKMT2AMEN1CNR1 | |
| SCHEMBL31282648 | 0.88 | USP30 (0.47) | USP30STSKMT2AMEN1CNR1 | |
| SCHEMBL31282918 | 0.88 | USP30 (0.47) | USP30STSKMT2AMEN1CNR1 | |
| SCHEMBL26274182 | 0.88 | USP30 (0.47) | USP30STSKMT2AMEN1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4472963-A1 | DGK TARGETING COMPOUNDS AND USES THEREOF | Arvinas Operations, Inc. (US) | 2024-12-11 | — | — | EP | disclosed |
| CN-118946556-A | DGK targeting compounds and uses thereof | 阿维纳斯运营公司 | 2024-11-12 | — | — | CN | disclosed |