Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | CACNB4 | O00305 | 2/20 | 0.45 |
| ▸ | CACNA1A | O00555 | 2/20 | 0.45 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.45 |
| ▸ | CACNG3 | O60359 | 2/20 | 0.45 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.45 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.45 |
| ▸ | CACNB3 | P54284 | 2/20 | 0.45 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.45 |
| ▸ | CACNG7 | P62955 | 2/20 | 0.45 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.45 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.45 |
| ▸ | CACNB1 | Q02641 | 2/20 | 0.45 |
| ▸ | CACNG1 | Q06432 | 2/20 | 0.45 |
| ▸ | CACNB2 | Q08289 | 2/20 | 0.45 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.45 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31282832 | 1.00 | MAPT (0.47) | MAPTUSP30PDE4BALDH1A1CACNB4 | |
| SCHEMBL25388905 | 1.00 | MAPT (0.47) | MAPTUSP30PDE4BALDH1A1CACNB4 | |
| SCHEMBL31288366 | 1.00 | MAPT (0.47) | MAPTUSP30PDE4BALDH1A1CACNB4 | |
| SCHEMBL31282640 | 1.00 | MAPT (0.47) | MAPTUSP30PDE4BALDH1A1CACNB4 | |
| SCHEMBL31282648 | 0.88 | USP30 (0.47) | MAPTUSP30ALDH1A1STSMEN1 | |
| SCHEMBL31283891 | 0.88 | USP30 (0.47) | MAPTUSP30ALDH1A1STSMEN1 | |
| SCHEMBL25387627 | 0.88 | STS (0.47) | MAPTUSP30ALDH1A1STSMEN1 | |
| SCHEMBL31282918 | 0.88 | USP30 (0.47) | MAPTUSP30ALDH1A1STSMEN1 | |
| SCHEMBL31282658 | 0.88 | USP30 (0.47) | MAPTUSP30ALDH1A1STSMEN1 | |
| SCHEMBL26274175 | 0.88 | USP30 (0.47) | MAPTUSP30ALDH1A1STSMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4472963-A1 | DGK TARGETING COMPOUNDS AND USES THEREOF | Arvinas Operations, Inc. (US) | 2024-12-11 | — | — | EP | disclosed |
| CN-118946556-A | DGK targeting compounds and uses thereof | 阿维纳斯运营公司 | 2024-11-12 | — | — | CN | disclosed |