Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 6/20 | 0.92 |
| ▸ | CTDSP1 | Q9GZU7 | 3/20 | 0.79 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.79 |
| ▸ | MAPT | P10636 | 1/20 | 0.79 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.79 |
| ▸ | PTGES | O14684 | 1/20 | 0.78 |
| ▸ | KAT2B | Q92831 | 5/20 | 0.75 |
| ▸ | CREBBP | Q92793 | 4/20 | 0.75 |
| ▸ | KAT2A | Q92830 | 4/20 | 0.75 |
| ▸ | EP300 | Q09472 | 3/20 | 0.75 |
| ▸ | MEN1 | O00255 | 4/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.62 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.62 |
| ▸ | APBA1 | Q02410 | 2/20 | 0.62 |
| ▸ | PTPN22 | Q9Y2R2 | 2/20 | 0.62 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.62 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14429922 | 0.91 | MAPT (0.81) | APEX1CTDSP1DUSP3MAPTMCL1 | |
| SCHEMBL31283567 | 0.90 | CTDSP1 (0.80) | APEX1CTDSP1DUSP3MAPTMCL1 | |
| SCHEMBL22260018 | 0.89 | APEX1 (0.79) | APEX1CTDSP1DUSP3MAPTMCL1 | |
| SCHEMBL31284992 | 0.88 | CTDSP1 (0.74) | APEX1CTDSP1DUSP3MAPTMCL1 | |
| SCHEMBL14430154 | 0.86 | MAPT (0.80) | APEX1CTDSP1DUSP3MAPTMCL1 | |
| SCHEMBL24518350 | 0.80 | MAPT (0.68) | APEX1CTDSP1DUSP3MAPTMCL1 | |
| SCHEMBL29727846 | 0.80 | MAPT (0.68) | APEX1CTDSP1DUSP3MAPTMCL1 | |
| SCHEMBL22259759 | 0.78 | APEX1 (0.60) | APEX1CTDSP1DUSP3MAPTMCL1 | |
| SCHEMBL22259817 | 0.78 | APEX1 (0.60) | APEX1CTDSP1DUSP3MAPTMCL1 | |
| SCHEMBL22259819 | 0.78 | APEX1 (0.60) | APEX1CTDSP1DUSP3MAPTMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024260410-A1 | OTUB2 INHIBITOR AND USE THEREOF IN TUMOR IMMUNITY | 厦门大学 | 2024-12-26 | — | — | WO | claimed |
| CN-119174818-A | OTUB2 inhibitor and application thereof in tumor immunity | 厦门大学 | 2024-12-24 | — | — | CN | claimed |
| WO-2024260410-A1 | OTUB2 INHIBITOR AND USE THEREOF IN TUMOR IMMUNITY | 厦门大学 | 2024-12-26 | — | — | WO | disclosed |
| CN-119174818-A | OTUB2 inhibitor and application thereof in tumor immunity | 厦门大学 | 2024-12-24 | — | — | CN | disclosed |