Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.49 |
| ▸ | NOTUM | Q6P988 | 10/20 | 0.48 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | CCR3 | P51677 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | MYC | P01106 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31284413 | 0.94 | NOTUM (0.53) | MRGPRX4NOTUMMALT1SLC6A2SLC6A4 | |
| SCHEMBL31285029 | 0.88 | MAPT (0.42) | MRGPRX4NOTUMMALT1SLC6A2SLC6A4 | |
| SCHEMBL31284943 | 0.88 | MAPT (0.42) | MRGPRX4NOTUMMALT1SLC6A2SLC6A4 | |
| SCHEMBL31284548 | 0.86 | MALT1 (0.48) | MRGPRX4NOTUMMALT1ALDH1A1HTR6 | |
| SCHEMBL31285356 | 0.86 | MALT1 (0.46) | MRGPRX4NOTUMMALT1HTR6 | |
| SCHEMBL31284479 | 0.84 | MALT1 (0.52) | MRGPRX4NOTUMMALT1HTR6KCNH2 | |
| SCHEMBL31284277 | 0.84 | MALT1 (0.45) | MRGPRX4NOTUMMALT1ALDH1A1HTR6 | |
| SCHEMBL31284753 | 0.84 | MALT1 (0.45) | MRGPRX4NOTUMMALT1SLC6A2SLC6A4 | |
| SCHEMBL31284365 | 0.82 | NOTUM (0.55) | MRGPRX4NOTUMMALT1SLC6A2SLC6A4 | |
| SCHEMBL31284720 | 0.82 | NOTUM (0.55) | MRGPRX4NOTUMMALT1ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119176772-A | Compound with Mrgpr X receptor inhibition effect and application thereof | 博济医药科技股份有限公司 | 2024-12-24 | — | — | CN | disclosed |