Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FASN | P49327 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | CETP | P11597 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.40 |
| ▸ | TP53 | P04637 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CEPT1 | Q9Y6K0 | 2/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24454912 | 1.00 | FASN (0.44) | FASNMAPTCETPRAB9ANPC1 | |
| SCHEMBL24454955 | 0.87 | MAPT (0.43) | FASNMAPTCETPRAB9ANPC1 | |
| SCHEMBL24454910 | 0.84 | CETP (0.44) | FASNMAPTCETPRAB9ANPC1 | |
| SCHEMBL24454878 | 0.83 | MAPT (0.47) | FASNMAPTCETPRAB9ANPC1 | |
| SCHEMBL29686567 | 0.83 | CETP (0.44) | FASNMAPTCETPRAB9ANPC1 | |
| SCHEMBL24454885 | 0.83 | CETP (0.44) | FASNMAPTCETPRAB9ANPC1 | |
| SCHEMBL24454899 | 0.83 | FASN (0.47) | FASNMAPTCETPRAB9ANPC1 | |
| SCHEMBL24454922 | 0.83 | MAPT (0.43) | MAPTRAB9ANPC1ALDH1A1KDM4E | |
| SCHEMBL24454956 | 0.82 | CETP (0.44) | FASNMAPTCETPRAB9ANPC1 | |
| SCHEMBL24454871 | 0.81 | FASN (0.58) | FASNMAPTCETPRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4247800-B1 | N-SUBSTITUTED 4-(1,3-ARYLOXAZOLO-2-YL)PHENYL COMPOUNDS FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION | HOFFMANN LA ROCHE (CH) | 2024-11-13 | — | — | EP | claimed |
| EP-4247800-B1 | N-SUBSTITUTED 4-(1,3-ARYLOXAZOLO-2-YL)PHENYL COMPOUNDS FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION | HOFFMANN LA ROCHE (CH) | 2024-11-13 | — | — | EP | disclosed |