Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD5 | P21918 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31284530 | 1.00 | NOTUM (0.46) | NOTUMMAPTSMN1; SMN2MALT1RAB9A | |
| SCHEMBL31285029 | 0.94 | MAPT (0.42) | NOTUMMAPTSMN1; SMN2MALT1RAB9A | |
| SCHEMBL31284943 | 0.94 | MAPT (0.42) | NOTUMMAPTSMN1; SMN2MALT1RAB9A | |
| SCHEMBL31284413 | 0.87 | NOTUM (0.53) | NOTUMMALT1HTR6TMEM97SIGMAR1 | |
| SCHEMBL31284595 | 0.86 | NOTUM (0.46) | NOTUMMAPTSMN1; SMN2MALT1RAB9A | |
| SCHEMBL31284297 | 0.85 | NOTUM (0.48) | NOTUMMAPTSMN1; SMN2MALT1RAB9A | |
| SCHEMBL31285341 | 0.85 | NOTUM (0.46) | NOTUMMAPTSMN1; SMN2MALT1RAB9A | |
| SCHEMBL31285385 | 0.85 | NOTUM (0.46) | NOTUMMAPTSMN1; SMN2MALT1RAB9A | |
| SCHEMBL31284657 | 0.84 | NOTUM (0.43) | NOTUMMALT1HTR6NPY5R | |
| SCHEMBL31284447 | 0.84 | NOTUM (0.45) | NOTUMMAPTSMN1; SMN2RAB9ASLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119176772-A | Compound with Mrgpr X receptor inhibition effect and application thereof | 博济医药科技股份有限公司 | 2024-12-24 | — | — | CN | disclosed |