SCHEMBL31286352

SCHEMBL31286352

CCCCCCCCCCCCCCCCCC[Si](I)(I)CCCCCCCCCCCCCCCCCC

nearest known ligand 0.50

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.50
THRB P10828 1/20 0.50
KCNH2 Q12809 1/20 0.41
DNM1 Q05193 6/20 0.38
ALDH1A1 P00352 3/20 0.38
LMNA P02545 2/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
HSD17B10 Q99714 1/20 0.38
SLC22A1 O15245 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18108229 1.00 TSHR (0.50) TSHRTHRBKCNH2DNM1ALDH1A1
SCHEMBL31286381 1.00 TSHR (0.50) TSHRTHRBKCNH2DNM1ALDH1A1
SCHEMBL18108440 1.00 TSHR (0.50) TSHRTHRBKCNH2DNM1ALDH1A1
SCHEMBL31286329 1.00 TSHR (0.50) TSHRTHRBKCNH2DNM1ALDH1A1
SCHEMBL31286349 1.00 TSHR (0.50) TSHRTHRBKCNH2DNM1ALDH1A1
SCHEMBL18108205 1.00 TSHR (0.50) TSHRTHRBKCNH2DNM1ALDH1A1
SCHEMBL18108447 0.97 TSHR (0.47) TSHRTHRBKCNH2DNM1ALDH1A1
SCHEMBL18108024 0.97 TSHR (0.47) TSHRTHRBKCNH2DNM1ALDH1A1
SCHEMBL1482529 0.87 TSHR (0.40) TSHRTHRBALDH1A1LMNASLC22A1
SCHEMBL20394659 0.84 TSHR (0.53) TSHRTHRBDNM1ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024232632-A1 TRANSITION METAL SUPPORTED CATALYST WITH IMPROVED HYDROGENATION ACTIVITY AND USE THEREOF 한양대학교 산학협력단 2024-11-14 WO claimed
WO-2024232632-A1 TRANSITION METAL SUPPORTED CATALYST WITH IMPROVED HYDROGENATION ACTIVITY AND USE THEREOF 한양대학교 산학협력단 2024-11-14 WO disclosed