Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | CLK2 | P49760 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | KHK | P50053 | 1/20 | 0.37 |
| ▸ | TERT | O14746 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31286931 | 0.89 | MAP3K5 (0.48) | MAP3K5L3MBTL1HTTLMNAKDM4E | |
| SCHEMBL31286952 | 0.81 | SMN1; SMN2 (0.50) | MAP3K5TP53L3MBTL1HTTLMNA | |
| SCHEMBL31286840 | 0.76 | MAP3K5 (0.56) | MAP3K5HTTLMNASMN1; SMN2KDM4E | |
| SCHEMBL17065991 | 0.76 | MAP3K5 (0.56) | MAP3K5SMN1; SMN2KDM4EROCK2 | |
| SCHEMBL25131709 | 0.74 | SMN1; SMN2 (0.48) | TP53L3MBTL1HTTLMNASMN1; SMN2 | |
| SCHEMBL17065980 | 0.72 | MAP3K5 (0.56) | MAP3K5TP53SMN1; SMN2KDM4EROCK2 | |
| SCHEMBL14247285 | 0.72 | MAP3K5 (0.61) | MAP3K5SMN1; SMN2KDM4EROCK2 | |
| SCHEMBL2947671 | 0.71 | MAP3K5 (0.64) | MAP3K5SMN1; SMN2KDM4E | |
| SCHEMBL17065938 | 0.71 | MAP3K5 (0.56) | MAP3K5 | |
| SCHEMBL31286867 | 0.70 | MAP3K5 (0.50) | MAP3K5LMNAKDM4ECLK2ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4747248-A1 | COMPOUNDS FOR USE IN A METHOD OF TARGETED PROTEIN DEGRADATION | Institute of Cancer Research: Royal Cancer Hospital (The) (GB) | 2026-05-27 | — | — | EP | disclosed |
| WO-2025022093-A1 | COMPOUNDS FOR USE IN A METHOD OF TARGETED PROTEIN DEGRADATION | THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (GB) | 2025-01-30 | — | — | WO | disclosed |