Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB4 | P30926 | 4/20 | 0.73 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.73 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.47 |
| ▸ | NOS3 | P29474 | 2/20 | 0.43 |
| ▸ | NOS1 | P29475 | 2/20 | 0.43 |
| ▸ | NOS2 | P35228 | 2/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | PTPRC | P08575 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14411431 | 0.93 | CHRNB4 (0.69) | CHRNB4CHRNA3HSP90AA1TSHRLMNA | |
| SCHEMBL28092025 | 0.92 | CHRNB4 (0.67) | CHRNB4CHRNA3HSP90AA1TSHRLMNA | |
| SCHEMBL2062764 | 0.84 | CHRNB4 (1.00) | CHRNB4CHRNA3CHRNB2CHRNA4 | |
| SCHEMBL5769693 | 0.84 | CHRNB4 (0.82) | CHRNB4CHRNA3HSP90AA1TSHRLMNA | |
| SCHEMBL29761230 | 0.84 | CHRNB4 (1.00) | CHRNB4CHRNA3CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL6392984 | 0.83 | CHRNB4 (0.82) | CHRNB4CHRNA3HSP90AA1TSHRLMNA | |
| Hydrochloric Acid SCHEMBL4405952 | 0.83 | CHRNB4 (1.00) | CHRNB4CHRNA3CHRNB2CHRNA4 | |
| SCHEMBL2062545 | 0.79 | CHRNB4 (0.60) | CHRNB4CHRNA3HSP90AA1LMNACHRNB2 | |
| SCHEMBL2060863 | 0.79 | CHRNB4 (0.52) | CHRNB4CHRNA3HSP90AA1LMNANOS3 | |
| SCHEMBL2061308 | 0.78 | CHRNB4 (0.58) | CHRNB4CHRNA3HSP90AA1TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8207207-B2 | Heterocyclic a amide derivatives useful as microbiocides | SYNGENTA CROP PROTECTION LLC (US) | 2012-06-26 | — | — | US | disclosed |
| US-8183416-B2 | Heterocyclic amide derivatives useful as microbiocides | SYNGENTA CROP PROTECTION, INC. (US) | 2012-05-22 | — | — | US | disclosed |
| EP-1940813-B1 | HETEROCYCLIC AMIDE DERIVATIVES USEFUL AS MICROBIOCIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2010-11-24 | — | — | EP | disclosed |
| US-20100204482-A1 | HETEROCYCLIC AMIDE DERIVATIVES USEFUL AS MICROBIOCIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-08-12 | — | — | US | disclosed |
| US-20100204287-A1 | HETEROCYCLIC AMIDE DERIVATIVES USEFUL AS MICROBIOCIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-08-12 | — | — | US | disclosed |
| EP-1940813-A1 | HETEROCYCLIC AMIDE DERIVATIVES USEFUL AS MICROBIOCIDES | Syngeta Participations AG (CH) | 2008-07-09 | — | — | EP | disclosed |
| WO-2007048556-A1 | HETEROCYCLIC AMIDE DERIVATIVES USEFUL AS MICROBIOCIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2007-05-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100204482-A1 | HETEROCYCLIC AMIDE DERIVATIVES USEFUL AS MICROBIOCIDES | CBR3, CBR1, CYP8B1 | CHRNB4 1695/4885CHRNA3 1945/4885HSP90AA1 1355/4885 |
| US-20100204287-A1 | HETEROCYCLIC AMIDE DERIVATIVES USEFUL AS MICROBIOCIDES | CBR3, CBR1, CYP8B1 | CHRNB4 1957/4885CHRNA3 2086/4885HSP90AA1 1177/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.