Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.54 |
| ▸ | ACE | P12821 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | THPO | P40225 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.39 |
| ▸ | FNTA | P49354 | 4/20 | 0.36 |
| ▸ | FNTB | P49356 | 4/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.34 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29567569 | 1.00 | PTGS1 (0.54) | PTGS1GSTK1ACEKDM4EMAPT | |
| SCHEMBL29567393 | 0.94 | PTGS1 (0.51) | PTGS1GSTK1ACEKDM4EMAPT | |
| SCHEMBL29567345 | 0.94 | PTGS1 (0.51) | PTGS1GSTK1ACEKDM4EMAPT | |
| SCHEMBL30484374 | 0.92 | PTGS1 (0.47) | PTGS1GSTK1ACEKDM4EMAPT | |
| SCHEMBL30392676 | 0.90 | PTGS1 (0.61) | PTGS1GSTK1ACEKDM4EMAPT | |
| SCHEMBL29532503 | 0.90 | PTGS1 (0.45) | PTGS1GSTK1ACEKDM4EMAPT | |
| SCHEMBL30730723 | 0.89 | ACE (0.49) | PTGS1GSTK1ACEKDM4EMAPT | |
| SCHEMBL7790449 | 0.88 | KDM4E (0.48) | PTGS1GSTK1ACEKDM4EMAPT | |
| SCHEMBL7790453 | 0.88 | KDM4E (0.48) | PTGS1GSTK1ACEKDM4EMAPT | |
| SCHEMBL29865388 | 0.88 | ACE (0.46) | PTGS1GSTK1ACEKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4746912-A1 | ORGANIC CYTOTOXIN OLIGOMERS AND USES THEREOF AS A PAYLOAD IN ANTIBODY-DRUG CONJUGATES | Simris Biologics GmbH (DE) | 2026-05-27 | — | — | EP | disclosed |
| WO-2025021727-A1 | ORGANIC CYTOTOXIN OLIGOMERS AND USES THEREOF AS A PAYLOAD IN ANTIBODY-DRUG CONJUGATES | SIMRIS BIOLOGICS GMBH (DE) | 2025-01-30 | — | — | WO | disclosed |
| EP-4494656-A1 | ORGANIC CYTOTOXIN OLIGOMERS AND USES THEREOF AS A PAYLOAD IN ANTIBODY-DRUG CONJUGATES | Simris Biologics GmbH (DE) | 2025-01-22 | — | — | EP | disclosed |