Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 20/20 | 0.66 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.60 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.60 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23880655 | 1.00 | EGFR (0.66) | EGFRERBB2ERBB3ERBB4 | |
| SCHEMBL17385141 | 0.93 | EGFR (0.63) | EGFRERBB2ERBB3ERBB4 | |
| SCHEMBL30748688 | 0.93 | EGFR (0.63) | EGFRERBB2ERBB3ERBB4 | |
| SCHEMBL29146006 | 0.92 | EGFR (0.56) | EGFRERBB2ERBB3ERBB4 | |
| SCHEMBL24464114 | 0.92 | EGFR (0.55) | EGFRERBB2ERBB3ERBB4 | |
| SCHEMBL19103269 | 0.91 | EGFR (0.57) | EGFRERBB2ERBB3ERBB4 | |
| SCHEMBL19103257 | 0.91 | EGFR (0.54) | EGFRERBB2ERBB3ERBB4 | |
| SCHEMBL28839358 | 0.91 | EGFR (0.57) | EGFRERBB2ERBB3ERBB4 | |
| SCHEMBL17384784 | 0.90 | EGFR (0.66) | EGFRERBB2ERBB3ERBB4 | |
| SCHEMBL24771072 | 0.90 | EGFR (0.53) | EGFRERBB2ERBB3ERBB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119219605-A | Bifunctional compound for targeted degradation of EGFR protein, and pharmaceutical composition, pharmaceutical preparation and application thereof | 北京福元医药股份有限公司 | 2024-12-31 | — | — | CN | disclosed |