Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | ERN1 | O75460 | 1/20 | 0.56 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | AR | P10275 | 2/20 | 0.53 |
| ▸ | IAPP | P10997 | 2/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31238165 | 0.85 | ERN1 (0.60) | MAPTERN1HSP90AA1MAPK1NPSR1 | |
| SCHEMBL3864314 | 0.84 | ERN1 (0.58) | MAPTLMNAERN1HSP90AA1MAPK1 | |
| SCHEMBL3864311 | 0.84 | ERN1 (0.58) | MAPTLMNAERN1HSP90AA1MAPK1 | |
| SCHEMBL30353437 | 0.82 | ERN1 (0.56) | MAPTERN1HSP90AA1MAPK1NPSR1 | |
| SCHEMBL13636232 | 0.82 | ERN1 (0.56) | MAPTERN1HSP90AA1MAPK1NPSR1 | |
| SCHEMBL19813877 | 0.82 | ERN1 (0.56) | MAPTERN1HSP90AA1MAPK1NPSR1 | |
| SCHEMBL26601267 | 0.81 | MAPT (0.67) | MAPTLMNAIAPPPTGS1KMT2A | |
| SCHEMBL10851425 | 0.81 | IAPP (0.55) | MAPTERN1HSP90AA1MAPK1NPSR1 | |
| SCHEMBL10851420 | 0.81 | IAPP (0.55) | MAPTERN1HSP90AA1MAPK1NPSR1 | |
| SCHEMBL11343002 | 0.80 | ERN1 (0.68) | MAPTLMNAERN1HSP90AA1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119219585-A | 3-Oxo propyl-2, 3-dihydrobenzofuran derivative with antibacterial activity, and preparation method and application thereof | 陕西科技大学 | 2024-12-31 | — | — | CN | claimed |
| CN-119219585-A | 3-Oxo propyl-2, 3-dihydrobenzofuran derivative with antibacterial activity, and preparation method and application thereof | 陕西科技大学 | 2024-12-31 | — | — | CN | disclosed |