Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 14/20 | 0.56 |
| ▸ | PIK3CA | P42336 | 7/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.56 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.56 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.56 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.56 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.56 |
| ▸ | PIK3R1 | P27986 | 3/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.56 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.56 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.56 |
| ▸ | PRKDC | P78527 | 1/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.56 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.56 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.56 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.56 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31290035 | 0.90 | MTOR (0.54) | MTORPIK3CAHDAC1PIK3CDPIK3CB | |
| SCHEMBL31290081 | 0.89 | PIK3CA (0.59) | MTORPIK3CAHDAC1PIK3CDPIK3CB | |
| SCHEMBL31290119 | 0.86 | PIK3CA (0.58) | MTORPIK3CAHDAC1PIK3CDPIK3CB | |
| SCHEMBL31290177 | 0.86 | PIK3CA (0.58) | MTORPIK3CAHDAC1PIK3CDPIK3CB | |
| SCHEMBL31290073 | 0.86 | PIK3CA (0.57) | MTORPIK3CAHDAC1PIK3CDPIK3CB | |
| SCHEMBL31290095 | 0.86 | PIK3CA (0.59) | MTORPIK3CAHDAC1PIK3CDPIK3CB | |
| SCHEMBL31290228 | 0.85 | PIK3CA (0.55) | MTORPIK3CAHDAC1PIK3CDPIK3CB | |
| SCHEMBL31290099 | 0.84 | PIK3CA (0.59) | MTORPIK3CAHDAC1PIK3CDPIK3CB | |
| SCHEMBL31290143 | 0.84 | PIK3CA (0.58) | MTORPIK3CAHDAC1PIK3CDPIK3CB | |
| SCHEMBL31290072 | 0.83 | PIK3CA (0.59) | MTORPIK3CAHDAC1PIK3CDPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119161359-A | Novel 4-morpholinyl thieno [3,2-d ] pyrimidine compound containing acrylamide structure and application thereof | 辽宁大学 | 2024-12-20 | — | — | CN | disclosed |