SCHEMBL31290185

SCHEMBL31290185

OC[C@H]1OC[C@@H](n2ncc3c(NC4CCCC4)nc(Cl)nc32)[C@H](O)[C@@H]1O

nearest known ligand 0.57

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
NT5E P21589 18/20 0.57
ADORA3 P0DMS8 1/20 0.51
ADORA2A P29274 1/20 0.51
ADORA2B P29275 1/20 0.51
ADORA1 P30542 1/20 0.51
MEN1 O00255 1/20 0.51
CYP1A2 P05177 1/20 0.51
MAPK1 P28482 1/20 0.51
KMT2A Q03164 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31290227 1.00 NT5E (0.57) NT5EADORA3ADORA2AADORA2BADORA1
SCHEMBL31290139 0.84 NT5E (0.78) NT5E
SCHEMBL23915097 0.84 NT5E (0.73) NT5EADORA3ADORA2AADORA2BADORA1
SCHEMBL19366702 0.84 NT5E (0.73) NT5EADORA3ADORA2AADORA2BADORA1
SCHEMBL24618960 0.82 NT5E (0.70) NT5E
SCHEMBL27414528 0.80 NT5E (0.52) NT5E
SCHEMBL19366711 0.80 NT5E (0.71) NT5EADORA3ADORA2AADORA2BADORA1
SCHEMBL27195239 0.79 NT5E (0.56) NT5EADORA3ADORA2AADORA2BADORA1
SCHEMBL30008197 0.79 NT5E (0.56) NT5EADORA3ADORA2AADORA2BADORA1
SCHEMBL22866496 0.78 NT5E (0.51) NT5E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119371459-A Compound and application thereof 重庆医药工业研究院有限责任公司 2025-01-28 CN disclosed