Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 11/20 | 0.60 |
| ▸ | MTOR | P42345 | 7/20 | 0.60 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.52 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.52 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.52 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.52 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.52 |
| ▸ | PRKACA | P17612 | 1/20 | 0.52 |
| ▸ | PRKACG | P22612 | 1/20 | 0.52 |
| ▸ | PRKACB | P22694 | 1/20 | 0.52 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.52 |
| ▸ | CDK2 | P24941 | 1/20 | 0.52 |
| ▸ | KDR | P35968 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | RAF1 | P04049 | 3/20 | 0.48 |
| ▸ | BRAF | P15056 | 2/20 | 0.48 |
| ▸ | PIKFYVE | Q9Y2I7 | 1/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.42 |
| ▸ | KIT | P10721 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24885831 | 1.00 | PIK3CA (0.60) | PIK3CAMTORPIK3R1PIK3CBPIK3CG | |
| SCHEMBL24885920 | 0.86 | RAF1 (0.53) | PIK3CAMTORPIK3R1PIK3CBPIK3CG | |
| SCHEMBL24885806 | 0.84 | PIK3CA (0.67) | PIK3CAMTORPIK3R1PIK3CBPIK3CG | |
| SCHEMBL30078287 | 0.84 | PIK3CA (0.67) | PIK3CAMTORPIK3R1PIK3CBPIK3CG | |
| SCHEMBL1864574 | 0.80 | PIK3CA (0.63) | PIK3CAMTORPIK3R1PIK3CBPIK3CG | |
| SCHEMBL1858784 | 0.78 | PIK3CA (0.66) | PIK3CAMTORPIK3R1PIK3CBPIK3CG | |
| SCHEMBL4440860 | 0.77 | PIK3CA (0.74) | PIK3CAMTORPIK3R1PIK3CBPIK3CG | |
| SCHEMBL24885730 | 0.76 | PIK3CA (0.73) | PIK3CAMTORPIK3R1PIK3CBPIK3CG | |
| SCHEMBL4436841 | 0.75 | PIK3CA (1.00) | PIK3CAMTORPIK3R1PIK3CBPIK3CG | |
| SCHEMBL12110480 | 0.73 | PIK3CA (0.72) | PIK3CAMTORPIK3R1PIK3CBPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240400577-A1 | MODULATORS OF PROTEIN KINASES | VIBLIOME THERAPEUTICS, LLC | 2024-12-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240400577-A1 | MODULATORS OF PROTEIN KINASES | MAP3K20, PRKCE, PRKCH | PIK3CA 218/4885MTOR 160/4885PIK3R1 341/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.