SCHEMBL31291015

SCHEMBL31291015

Fc1ccc(-c2cc(-c3ccc(-c4ccccc4)cc3)cc(-c3ccccc3)n2)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.65
KDM4E B2RXH2 1/20 0.65
TOP1 P11387 2/20 0.55
L3MBTL1 Q9Y468 2/20 0.54
MAPK1 P28482 1/20 0.54
HTT P42858 1/20 0.54
NPSR1 Q6W5P4 1/20 0.54
CYP19A1 P11511 2/20 0.53
ALDH1A3 P47895 1/20 0.53
LTB4R Q15722 1/20 0.52
MEN1 O00255 3/20 0.52
KMT2A Q03164 3/20 0.52
HPGD P15428 2/20 0.52
ALDH1A1 P00352 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
DHODH Q02127 1/20 0.51
ADORA2A P29274 1/20 0.51
ADORA1 P30542 1/20 0.51
MKNK1 Q9BUB5 1/20 0.49
MKNK2 Q9HBH9 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4355827 1.00 MAPT (0.65) MAPTKDM4ETOP1L3MBTL1MAPK1
SCHEMBL28196237 1.00 MAPT (0.65) MAPTKDM4ETOP1L3MBTL1MAPK1
SCHEMBL4001714 0.91 KDM4E (0.53) MAPTKDM4ETOP1L3MBTL1MAPK1
SCHEMBL10051450 0.89 CYP19A1 (0.63) MAPTKDM4EL3MBTL1CYP19A1MEN1
SCHEMBL4404689 0.89 CYP19A1 (0.63) MAPTKDM4EL3MBTL1CYP19A1MEN1
SCHEMBL19860206 0.89 CYP19A1 (0.63) MAPTKDM4EL3MBTL1CYP19A1MEN1
SCHEMBL10051444 0.89 CYP19A1 (0.63) MAPTKDM4EL3MBTL1CYP19A1MEN1
SCHEMBL10051447 0.89 CYP19A1 (0.63) MAPTKDM4EL3MBTL1CYP19A1MEN1
SCHEMBL12258341 0.89 CYP19A1 (0.63) MAPTKDM4EL3MBTL1CYP19A1MEN1
SCHEMBL22208326 0.89 MAPT (0.54) MAPTKDM4ETOP1L3MBTL1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240365658-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-10-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240365658-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, OR10J3 MAPT 652/4885KDM4E 3349/4885TOP1 4848/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.