Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | TP53 | P04637 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | SPR | P35270 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13521726 | 0.89 | MEN1 (0.52) | MEN1KMT2ATP53POLBMAPT | |
| SCHEMBL13521633 | 0.89 | TP53 (0.46) | MEN1KMT2ATP53POLBMAPT | |
| SCHEMBL3246664 | 0.87 | MEN1 (0.41) | MEN1KMT2ATP53POLBMAPT | |
| SCHEMBL13521594 | 0.86 | MEN1 (0.48) | MEN1KMT2ATP53POLBALDH1A1 | |
| SCHEMBL3246859 | 0.86 | MEN1 (0.40) | MEN1KMT2ATP53POLBMAPT | |
| SCHEMBL13521709 | 0.85 | TP53 (0.43) | MEN1KMT2ATP53POLBMAPT | |
| SCHEMBL13521729 | 0.84 | MEN1 (0.39) | MEN1KMT2ATP53POLBNPSR1 | |
| SCHEMBL13521716 | 0.84 | MEN1 (0.40) | MEN1KMT2ATP53POLBMAPT | |
| SCHEMBL13521727 | 0.83 | MEN1 (0.39) | MEN1KMT2ATP53POLBMAPT | |
| SCHEMBL3250703 | 0.82 | GRIN2B (0.40) | MEN1KMT2ATP53POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010008777-A2 | FUSED AZABICYCLIC PYRIDINES | LIGAND PHARMACEUTICALS INC. (US) | 2010-01-21 | — | — | WO | claimed |