Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 10/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15124774 | 0.89 | AAK1 (0.45) | AAK1CTSBCTSSCTSKMEN1 | |
| SCHEMBL244890 | 0.89 | AAK1 (0.45) | AAK1CTSBCTSSCTSKMEN1 | |
| SCHEMBL243147 | 0.87 | AAK1 (0.43) | AAK1CTSBCTSSCTSKMEN1 | |
| SCHEMBL31292821 | 0.86 | AAK1 (0.45) | AAK1CTSBCTSSCTSKMEN1 | |
| SCHEMBL2175047 | 0.85 | AAK1 (0.42) | AAK1CTSBCTSSCTSKMEN1 | |
| SCHEMBL31292779 | 0.84 | MAPK1 (0.36) | AAK1SMN1; SMN2ALDH1A1 | |
| SCHEMBL2580865 | 0.83 | AAK1 (0.45) | AAK1CTSBCTSSCTSKMEN1 | |
| SCHEMBL245817 | 0.81 | AAK1 (0.39) | AAK1CTSBCTSSCTSKMEN1 | |
| SCHEMBL6009498 | 0.80 | AAK1 (0.42) | AAK1CTSBCTSSCTSKMEN1 | |
| SCHEMBL15124834 | 0.80 | AAK1 (0.43) | AAK1CTSBCTSSCTSKMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025024030-A2 | MOLECULAR GLUES TARGETING A TRANSCRIPTIONAL REGULATOR OF ABERRANT METABOLIC STATES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2025-01-30 | — | — | WO | disclosed |