Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13447836 | 0.88 | KMT2A (0.57) | KMT2AMEN1TDP1MAPTHSP90AA1 | |
| SCHEMBL12418678 | 0.86 | MEN1 (0.56) | KMT2AMEN1TDP1MAPTHSP90AA1 | |
| SCHEMBL12394776 | 0.83 | KMT2A (0.60) | KMT2AMEN1TDP1MAPTHSP90AA1 | |
| SCHEMBL13447835 | 0.81 | MEN1 (0.56) | KMT2AMEN1TDP1MAPTHSP90AA1 | |
| SCHEMBL3119229 | 0.81 | MAPT (0.57) | KMT2AMEN1MAPTHSP90AA1CYP19A1 | |
| SCHEMBL1964298 | 0.80 | MEN1 (0.57) | KMT2AMEN1TDP1MAPTHSP90AA1 | |
| SCHEMBL12418677 | 0.80 | MEN1 (0.74) | KMT2AMEN1TDP1MAPTHSP90AA1 | |
| SCHEMBL12418543 | 0.79 | MEN1 (0.58) | KMT2AMEN1TDP1MAPTHSP90AA1 | |
| SCHEMBL3119242 | 0.78 | MEN1 (0.54) | KMT2AMEN1TDP1MAPTHSP90AA1 | |
| SCHEMBL12418541 | 0.78 | KMT2A (0.60) | KMT2AMEN1TDP1MAPTHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010031842-A1 | IMIDAZOLE AND TRIAZOLE COMPOUNDS, THEIR USE AND AGENTS CONTAINING THE SAME | BASF SE (DE) | 2010-03-25 | — | — | WO | disclosed |