SCHEMBL31293700

SCHEMBL31293700

CC(C)(C)OC(=O)N1CC2(CC(NCC(F)(F)F)C2)C1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EHMT2 Q96KQ7 1/20 0.40
EPHX2 P34913 2/20 0.39
EPHX1 P07099 1/20 0.37
NR1H2 P55055 1/20 0.37
RORC P51449 1/20 0.35
USP2 O75604 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
DDB1 Q16531 1/20 0.34
CRBN Q96SW2 1/20 0.34
OXTR P30559 1/20 0.34
AVPR1A P37288 1/20 0.34
TNF P01375 1/20 0.34
IRAK4 Q9NWZ3 1/20 0.34
ALDH1A1 P00352 2/20 0.33
HPGD P15428 1/20 0.33
KRAS P01116 1/20 0.33
NPC1 O15118 1/20 0.33
MAPT P10636 1/20 0.33
MAPK1 P28482 1/20 0.33
HTT P42858 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29589011 0.89 EHMT2 (0.41) EHMT2EPHX2EPHX1NR1H2USP2
SCHEMBL29589321 0.87 EPHX2 (0.40) EHMT2EPHX2EPHX1NR1H2RORC
SCHEMBL29588616 0.85 EHMT2 (0.41) EHMT2EPHX2EPHX1NR1H2RORC
SCHEMBL29589514 0.84 EHMT2 (0.40) EHMT2EPHX2EPHX1NR1H2USP2
SCHEMBL29588767 0.84 EHMT2 (0.40) EHMT2EPHX2EPHX1NR1H2RORC
SCHEMBL29589506 0.82 EHMT2 (0.40) EHMT2EPHX2EPHX1NR1H2RORC
SCHEMBL20301757 0.82 EHMT2 (0.40) EHMT2EPHX2EPHX1NR1H2USP2
SCHEMBL29588885 0.82 EHMT2 (0.38) EHMT2EPHX2EPHX1NR1H2RORC
SCHEMBL29588718 0.81 NR1H2 (0.43) EHMT2EPHX2EPHX1NR1H2SMN1; SMN2
SCHEMBL29589150 0.80 EHMT2 (0.39) EHMT2EPHX2EPHX1NR1H2USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4724439-A1 HETEROARYL DERIVATIVES AS DDRS INHIBITORS Chiesi Farmaceutici S.p.A. (IT) 2026-04-15 EP disclosed
WO-2024251855-A1 HETEROARYL DERIVATIVES AS DDRS INHIBITORS CHIESI FARMACEUTICI S.P.A. (IT) 2024-12-12 WO disclosed