SCHEMBL31294792

SCHEMBL31294792

CC(O)(CC(=O)O)c1ccc(F)c(F)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNN4 O15554 1/20 0.46
CYP2C19 P33261 1/20 0.43
HIF1A Q16665 1/20 0.43
MIF P14174 1/20 0.42
AKR1C3 P42330 2/20 0.41
AKR1C2 P52895 2/20 0.41
HDAC3 O15379 1/20 0.40
HDAC1 Q13547 1/20 0.40
HDAC2 Q92769 1/20 0.40
HDAC6 Q9UBN7 1/20 0.40
SLC13A5 Q86YT5 2/20 0.40
HMGCR P04035 1/20 0.39
CHRM1 P11229 1/20 0.39
TBXA2R P21731 1/20 0.39
ADRA1A P35348 1/20 0.39
APP P05067 1/20 0.39
CES2 O00748 1/20 0.38
CES1 P23141 1/20 0.38
RIPK1 Q13546 1/20 0.38
CHRM3 P20309 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31294831 0.81 HPGD (0.38) KCNN4RIPK1
SCHEMBL17582914 0.79 CYP2C19 (0.47) KCNN4CYP2C19HIF1AMIFHDAC6
SCHEMBL17582917 0.79 CYP2C19 (0.47) KCNN4CYP2C19HIF1AMIFHDAC6
SCHEMBL6961485 0.78 CHRM3 (0.42) KCNN4AKR1C3AKR1C2HDAC3HDAC1
SCHEMBL1627216 0.76 AKR1C3 (0.64) KCNN4AKR1C3AKR1C2HDAC3HDAC1
SCHEMBL24020497 0.76 MIF (0.66) CYP2C19HIF1AMIFSLC13A5HMGCR
SCHEMBL4453210 0.76 HMGCR (0.43) CYP2C19HIF1AMIFHDAC6SLC13A5
SCHEMBL4467346 0.76 HMGCR (0.43) CYP2C19HIF1AMIFHDAC6SLC13A5
SCHEMBL11833099 0.75 BCL2L1 (0.46) KCNN4CYP2C19HIF1ASLC13A5HMGCR
SCHEMBL6967423 0.74 KCNN4 (0.43) KCNN4AKR1C3AKR1C2HDAC3HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4735423-A1 KV7 MODULATORS Saniona A/S (DK) 2026-05-06 EP disclosed
WO-2025003343-A1 KV7 MODULATORS SANIONA A/S (DK) 2025-01-02 WO disclosed