Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WRN | Q14191 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31295782 | 0.93 | WRN (0.48) | WRNACHEALDH1A1MAPTCYP3A4 | |
| SCHEMBL31295769 | 0.89 | WRN (0.48) | WRNACHEALDH1A1MAPTPOLB | |
| SCHEMBL31295853 | 0.89 | WRN (0.48) | WRNACHEALDH1A1MAPTPOLB | |
| SCHEMBL31295796 | 0.87 | WRN (0.61) | WRNACHEALDH1A1MAPTPOLB | |
| SCHEMBL31295872 | 0.87 | WRN (0.44) | WRNACHE | |
| SCHEMBL31295795 | 0.87 | WRN (0.55) | WRNACHEALDH1A1MAPTPOLB | |
| SCHEMBL31295801 | 0.86 | WRN (0.50) | WRNACHEALDH1A1MAPTPOLB | |
| SCHEMBL31295763 | 0.86 | WRN (0.50) | WRNACHEALDH1A1MAPTPOLB | |
| SCHEMBL30984140 | 0.85 | WRN (0.53) | WRNACHESCN9AALDH1A1MAPT | |
| SCHEMBL30984267 | 0.83 | WRN (0.58) | WRNACHESCN9AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4735447-A1 | AROMATIC NITROGEN-CONTAINING COMPOUNDS, PREPARATION METHODS AND MEDICINAL USES THEREOF | Jiangsu Hengrui Pharmaceuticals Co., Ltd. (CN) | 2026-05-06 | — | — | EP | disclosed |
| WO-2025002413-A1 | AROMATIC NITROGEN-CONTAINING COMPOUNDS, PREPARATION METHODS AND MEDICINAL USES THEREOF | SHANGHAI HANSOH BIOMEDICAL CO., LTD. (CN) | 2025-01-02 | — | — | WO | disclosed |