Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WRN | Q14191 | 1/20 | 0.57 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30038447 | 0.96 | WRN (0.61) | WRNACHEPOLBL3MBTL1ALDH1A1 | |
| SCHEMBL25036852 | 0.96 | WRN (0.61) | WRNACHEPOLBL3MBTL1ALDH1A1 | |
| SCHEMBL31295811 | 0.89 | WRN (0.54) | WRNACHEPOLBL3MBTL1ALDH1A1 | |
| SCHEMBL31295764 | 0.87 | WRN (0.49) | WRNACHEPOLBL3MBTL1ALDH1A1 | |
| SCHEMBL31295832 | 0.87 | WRN (0.64) | WRNACHEPOLBL3MBTL1ALDH1A1 | |
| SCHEMBL31295794 | 0.85 | WRN (0.49) | WRNACHEPOLBL3MBTL1ALDH1A1 | |
| SCHEMBL31295756 | 0.85 | WRN (0.47) | WRNACHEPOLBL3MBTL1ALDH1A1 | |
| SCHEMBL30984247 | 0.85 | WRN (0.49) | WRNPOLBL3MBTL1ALDH1A1TSHR | |
| SCHEMBL31713883 | 0.85 | WRN (0.49) | WRNPOLBKDM4ECYP1A2CYP3A4 | |
| SCHEMBL31295758 | 0.84 | WRN (0.47) | WRNACHEPOLBL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4735447-A1 | AROMATIC NITROGEN-CONTAINING COMPOUNDS, PREPARATION METHODS AND MEDICINAL USES THEREOF | Jiangsu Hengrui Pharmaceuticals Co., Ltd. (CN) | 2026-05-06 | — | — | EP | disclosed |
| WO-2025002413-A1 | AROMATIC NITROGEN-CONTAINING COMPOUNDS, PREPARATION METHODS AND MEDICINAL USES THEREOF | SHANGHAI HANSOH BIOMEDICAL CO., LTD. (CN) | 2025-01-02 | — | — | WO | disclosed |