Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN2A | Q99250 | 3/20 | 0.72 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.51 |
| ▸ | HTR3A | P46098 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | DPP4 | P27487 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HRH2 | P25021 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | NEK2 | P51955 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL603266 | 0.86 | SCN2A (0.70) | SCN2AHRH4HTR3AHRH3 | |
| SCHEMBL605612 | 0.86 | SCN2A (0.61) | SCN2AHRH4HSD17B10TSHRUSP2 | |
| SCHEMBL31295973 | 0.85 | SCN2A (0.69) | SCN2AHRH4HTR3AHSD17B10TSHR | |
| SCHEMBL31295935 | 0.85 | SCN2A (0.66) | SCN2AHRH4HTR3AHSD17B10TSHR | |
| Hydrochloric Acid SCHEMBL604645 | 0.85 | SCN2A (0.60) | SCN2AHRH4HSD17B10TSHRUSP2 | |
| SCHEMBL31296003 | 0.84 | SCN2A (0.64) | SCN2AHRH4HTR3AHSD17B10TSHR | |
| SCHEMBL31295948 | 0.84 | SCN2A (0.74) | SCN2AHRH4HTR3AHSD17B10TSHR | |
| SCHEMBL31295959 | 0.83 | SCN2A (0.72) | SCN2AHRH4HTR3AHSD17B10TSHR | |
| SCHEMBL2166625 | 0.82 | HRH4 (0.76) | SCN2AHRH4HTR3A | |
| SCHEMBL31295953 | 0.81 | SCN2A (0.60) | SCN2AHRH4HSD17B10TSHRUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119119003-A | Pyrimidine amine-containing compound, preparation method, pharmaceutical composition and application thereof | 国科大杭州高等研究院 | 2024-12-13 | — | — | CN | claimed |