SCHEMBL31296475

SCHEMBL31296475

CCCCC#CC1C=CC=CC1c1ccccc1

nearest known ligand 0.33

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 2/20 0.32
CYP3A4 P08684 2/20 0.32
CYP2C9 P11712 2/20 0.32
CYP2C19 P33261 2/20 0.32
KDM4E B2RXH2 1/20 0.32
LMNA P02545 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2D6 P10635 1/20 0.32
MAPT P10636 1/20 0.32
APEX1 P27695 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HSD17B10 Q99714 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
KCNH2 Q12809 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31296442 0.68 PTPN7 (0.32) CYP3A4CYP2C19KDM4ECYP2D6MAPT
SCHEMBL4255092 0.66 CUL4A (0.33) KDM4EMAPTHSD17B10TDP1
Hydrochloric Acid SCHEMBL4688615 0.65 CUL4A (0.32) KDM4ELMNAMAPTHSD17B10TDP1
SCHEMBL30311727 0.64 RECQL (0.40) CYP3A4CYP2C9CYP2C19LMNACYP1A2
SCHEMBL31296450 0.63
SCHEMBL31296503 0.63
SCHEMBL614578 0.63 CYP1A2 (0.50) CYP3A4CYP2C9CYP2C19KDM4ELMNA
SCHEMBL31296407 0.62 TSHR (0.30) TDP1
Hydrochloric Acid SCHEMBL31144511 0.61 BLM (0.52) CYP3A4CYP2C9CYP2C19KDM4ELMNA
SCHEMBL22731174 0.61 KCNH2 (0.59) KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119219681-A Method for synthesizing axial chiral organoboron compounds 合成化学暨分子生物学有限公司 2024-12-31 CN disclosed