Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 18/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 13/20 | 0.49 |
| ▸ | PDE4A | P27815 | 10/20 | 0.49 |
| ▸ | PDE4C | Q08493 | 10/20 | 0.49 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | PDE5A | O76074 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3129681 | 0.91 | PDE4D (0.50) | PDE4DPDE4BPDE4APDE4CABCB11 | |
| SCHEMBL3131858 | 0.90 | PDE4D (0.52) | PDE4DPDE4BPDE4APDE4CABCB11 | |
| SCHEMBL3129536 | 0.89 | PDE4D (0.46) | PDE4DPDE4BPDE4APDE4CABCB11 | |
| SCHEMBL3131490 | 0.88 | PDE4D (0.52) | PDE4DPDE4BPDE4APDE4CABCB11 | |
| SCHEMBL3129434 | 0.87 | KMT2A (0.37) | PDE4DPDE4BPDE4APDE4C | |
| SCHEMBL3130954 | 0.87 | PDE4B (0.48) | PDE4DPDE4BPDE4APDE4CABCB11 | |
| SCHEMBL3122581 | 0.81 | PDE4D (0.45) | PDE4DPDE4BPDE4APDE4CABCB11 | |
| SCHEMBL3132484 | 0.81 | PDE4D (0.39) | PDE4DPDE4BPDE4APDE4C | |
| SCHEMBL3132792 | 0.80 | KMT2A (0.36) | PDE4DPDE4BPDE4APDE4C | |
| SCHEMBL1157297 | 0.79 | PDE4D (0.54) | PDE4DPDE4BPDE4APDE4CABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010003084-A2 | PHOSPHODIESTERASE 4 INHIBITORS | MEMORY PHARMACEUTICALS CORPORATION (US) | 2010-01-07 | — | — | WO | disclosed |