Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN8A | Q9UQD0 | 3/20 | 0.64 |
| ▸ | SCN10A | Q9Y5Y9 | 3/20 | 0.64 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20638950 | 1.00 | SCN8A (0.64) | SCN8ASCN10ALRRK2 | |
| SCHEMBL31297268 | 0.92 | SCN8A (0.64) | SCN8ASCN10A | |
| SCHEMBL20644197 | 0.92 | SCN8A (0.64) | SCN8ASCN10A | |
| SCHEMBL20644110 | 0.92 | SCN8A (0.65) | SCN8ASCN10ALRRK2 | |
| SCHEMBL13852931 | 0.89 | RXFP1 (0.62) | SCN8ASCN10A | |
| SCHEMBL20644112 | 0.87 | SCN8A (0.66) | SCN8ASCN10A | |
| SCHEMBL30530128 | 0.87 | SCN8A (0.66) | SCN8ASCN10A | |
| SCHEMBL20644053 | 0.87 | SCN8A (0.68) | SCN8ASCN10A | |
| SCHEMBL20644021 | 0.87 | SCN8A (0.66) | SCN8ASCN10ALRRK2 | |
| SCHEMBL20644071 | 0.86 | SCN8A (0.67) | SCN8ASCN10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3651752-B1 | CARBOXAMIDES AS MODULATORS OF SODIUM CHANNELS | VERTEX PHARMA (US) | 2024-11-20 | — | — | EP | disclosed |