Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.30 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31297604 | 0.77 | CYP19A1 (0.46) | NPC1MAPTRAB9AGFERSMN1; SMN2 | |
| SCHEMBL31324862 | 0.76 | CCNC (0.47) | NPC1RAB9ASMN1; SMN2PDE3BPDE3A | |
| SCHEMBL31297716 | 0.75 | CCNC (0.44) | NPC1MAPTRAB9AGFERSMN1; SMN2 | |
| SCHEMBL31297632 | 0.74 | SMN1; SMN2 (0.43) | NPC1MAPTRAB9ASMN1; SMN2CYP19A1 | |
| SCHEMBL31297623 | 0.74 | CCNC (0.47) | NPC1MAPTRAB9AGFERSMN1; SMN2 | |
| SCHEMBL31297653 | 0.73 | CCNC (0.36) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL31297659 | 0.73 | MAPK1 (0.33) | NPC1MAPTRAB9AGFERSMN1; SMN2 | |
| SCHEMBL31297678 | 0.73 | KIT (0.39) | CYP19A1 | |
| SCHEMBL31297547 | 0.72 | MAPT (0.45) | NPC1MAPTRAB9AGFERSMN1; SMN2 | |
| SCHEMBL31297648 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4735114-A1 | SUBSTITUTED THIENO [3,2-B]PYRIDINES AS INHIBITORS OF PROTEIN KINASES | Masarykova Univerzita (CZ) | 2026-05-06 | — | — | EP | disclosed |
| WO-2025002491-A1 | SUBSTITUTED THIENO [3,2-B]PYRIDINES AS INHIBITORS OF PROTEIN KINASES | MASARYKOVA UNIVERZITA (CZ) | 2025-01-02 | — | — | WO | disclosed |
| EP-4483954-A1 | SUBSTITUTED THIENO [3,2-B]PYRIDINES AS INHIBITORS OF PROTEIN KINASES | Masarykova Univerzita (CZ) | 2025-01-01 | — | — | EP | disclosed |