Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACVR2A | P27037 | 15/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | TGFBR2 | P37173 | 14/20 | 0.43 |
| ▸ | CLK1 | P49759 | 2/20 | 0.42 |
| ▸ | CLK2 | P49760 | 2/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.42 |
| ▸ | HIPK1 | Q86Z02 | 2/20 | 0.42 |
| ▸ | DYRK2 | Q92630 | 2/20 | 0.42 |
| ▸ | HIPK2 | Q9H2X6 | 2/20 | 0.42 |
| ▸ | HIPK3 | Q9H422 | 2/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.42 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | HIPK4 | Q8NE63 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31297664 | 0.87 | DYRK1A (0.45) | MAPTCLK1CLK2DYRK1AHIPK1 | |
| SCHEMBL31297588 | 0.86 | MAPT (0.45) | MAPTCLK1CLK2DYRK1AHIPK1 | |
| Hydrochloric Acid SCHEMBL31324880 | 0.86 | DYRK1A (0.44) | MAPTCLK1CLK2DYRK1AHIPK1 | |
| SCHEMBL31297577 | 0.85 | DYRK1A (0.44) | ACVR2AMAPTCLK1CLK2DYRK1A | |
| SCHEMBL31297587 | 0.85 | DYRK1A (0.44) | ACVR2AMAPTCLK1CLK2DYRK1A | |
| SCHEMBL31297612 | 0.85 | DYRK1A (0.44) | MAPTCLK1CLK2DYRK1AHIPK1 | |
| SCHEMBL31297553 | 0.84 | CLK2 (0.45) | MAPTCLK1CLK2DYRK1AHIPK1 | |
| SCHEMBL31297582 | 0.82 | DYRK1A (0.42) | MAPTCLK1CLK2DYRK1AHIPK1 | |
| SCHEMBL31297646 | 0.82 | DYRK1A (0.51) | MAPTCLK1CLK2DYRK1AHIPK1 | |
| SCHEMBL31297690 | 0.82 | DYRK1A (0.45) | CLK1CLK2DYRK1AHIPK1DYRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4735114-A1 | SUBSTITUTED THIENO [3,2-B]PYRIDINES AS INHIBITORS OF PROTEIN KINASES | Masarykova Univerzita (CZ) | 2026-05-06 | — | — | EP | disclosed |
| WO-2025002491-A1 | SUBSTITUTED THIENO [3,2-B]PYRIDINES AS INHIBITORS OF PROTEIN KINASES | MASARYKOVA UNIVERZITA (CZ) | 2025-01-02 | — | — | WO | disclosed |
| EP-4483954-A1 | SUBSTITUTED THIENO [3,2-B]PYRIDINES AS INHIBITORS OF PROTEIN KINASES | Masarykova Univerzita (CZ) | 2025-01-01 | — | — | EP | disclosed |