Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 7/20 | 0.42 |
| ▸ | CLK2 | P49760 | 7/20 | 0.42 |
| ▸ | HIPK1 | Q86Z02 | 7/20 | 0.42 |
| ▸ | HIPK2 | Q9H2X6 | 7/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 7/20 | 0.42 |
| ▸ | CLK1 | P49759 | 6/20 | 0.42 |
| ▸ | HIPK3 | Q9H422 | 6/20 | 0.42 |
| ▸ | DYRK1B | Q9Y463 | 4/20 | 0.42 |
| ▸ | DYRK2 | Q92630 | 3/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | HIPK4 | Q8NE63 | 1/20 | 0.42 |
| ▸ | FYN | P06241 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CCNC | P24863 | 4/20 | 0.38 |
| ▸ | CDK8 | P49336 | 4/20 | 0.38 |
| ▸ | CLK3 | P49761 | 2/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.36 |
| ▸ | GRK5 | P34947 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31297553 | 0.90 | CLK2 (0.45) | DYRK1ACLK2HIPK1HIPK2CLK4 | |
| SCHEMBL31297646 | 0.88 | DYRK1A (0.51) | DYRK1ACLK2HIPK1HIPK2CLK4 | |
| SCHEMBL31297702 | 0.87 | DYRK1A (0.54) | DYRK1ACLK2HIPK1HIPK2CLK4 | |
| SCHEMBL31297664 | 0.86 | DYRK1A (0.45) | DYRK1ACLK2HIPK1HIPK2CLK4 | |
| SCHEMBL31297661 | 0.85 | DYRK1A (0.47) | DYRK1ACLK2HIPK1HIPK2CLK4 | |
| SCHEMBL31297605 | 0.85 | DYRK1A (0.43) | DYRK1ACLK2HIPK1HIPK2CLK4 | |
| Hydrochloric Acid SCHEMBL31324880 | 0.85 | DYRK1A (0.44) | DYRK1ACLK2HIPK1HIPK2CLK4 | |
| SCHEMBL31324902 | 0.83 | CLK2 (0.41) | DYRK1ACLK2HIPK1HIPK2CLK4 | |
| SCHEMBL31297603 | 0.83 | DYRK1A (0.43) | DYRK1ACLK2HIPK1HIPK2CLK4 | |
| SCHEMBL31297596 | 0.83 | MKNK1 (0.44) | DYRK1ACLK2HIPK1HIPK2CLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4735114-A1 | SUBSTITUTED THIENO [3,2-B]PYRIDINES AS INHIBITORS OF PROTEIN KINASES | Masarykova Univerzita (CZ) | 2026-05-06 | — | — | EP | disclosed |
| WO-2025002491-A1 | SUBSTITUTED THIENO [3,2-B]PYRIDINES AS INHIBITORS OF PROTEIN KINASES | MASARYKOVA UNIVERZITA (CZ) | 2025-01-02 | — | — | WO | disclosed |
| EP-4483954-A1 | SUBSTITUTED THIENO [3,2-B]PYRIDINES AS INHIBITORS OF PROTEIN KINASES | Masarykova Univerzita (CZ) | 2025-01-01 | — | — | EP | disclosed |