⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32672749 | 0.88 | HTR2A (0.30) | — | |
| SCHEMBL32672783 | 0.87 | SLC6A2 (0.31) | — | |
| SCHEMBL32672759 | 0.87 | SLC6A2 (0.31) | — | |
| SCHEMBL32672908 | 0.81 | LOX (0.34) | — | |
| SCHEMBL32673011 | 0.81 | CTSA (0.37) | — | |
| SCHEMBL32673132 | 0.80 | — | — | |
| SCHEMBL32673024 | 0.80 | SLC6A2 (0.31) | — | |
| SCHEMBL32673192 | 0.80 | SLC6A2 (0.32) | — | |
| SCHEMBL32672938 | 0.79 | SLC6A2 (0.33) | — | |
| SCHEMBL32673152 | 0.79 | SLC6A2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4698524-A1 | TRIARYL AGONISTS OF ALPHA-2 ADRENERGIC RECEPTORS | Alceptor Therapeutics, Inc. (US) | 2026-02-25 | — | — | EP | disclosed |
| US-20260042769-A1 | TRIARYL AGONISTS OF ALPHA-2 ADRENERGIC RECEPTORS | ALCEPTOR THERAPEUTICS INC (US) | 2026-02-12 | — | — | US | disclosed |
| WO-2024220941-A1 | TRIARYL AGONISTS OF ALPHA-2 ADRENERGIC RECEPTORS | ALCEPTOR THERAPEUTICS, INC. (US) | 2024-10-24 | — | — | WO | disclosed |