SCHEMBL31299

SCHEMBL31299

[CH]1OCO1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3387 0.80
SCHEMBL1322917 0.72
SCHEMBL51249 0.68
SCHEMBL10974671 0.68
SCHEMBL76442 0.63
SCHEMBL13255034 0.63
SCHEMBL39285 0.63
SCHEMBL1190870 0.57
SCHEMBL57118 0.54
SCHEMBL2554291 0.54

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 954 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240190869-A1 5,7-DIHYDRO-PYRROLO-PYRIDINE DERIVATIVES PFIZER (US) 2024-06-13 US claimed
US-20240182416-A1 DERIVATIVES OF ARYL HYDROCARBON RECEPTOR AGONISTS AZORA THERAPEUTICS, INC. 2024-06-06 US claimed
US-11834412-B2 Derivatives of aryl hydrocarbon receptor agonists AZORA THERAPEUTICS, INC. (US) 2023-12-05 US claimed
US-20230192690-A1 5,7-DIHYDRO-PYRROLO-PYRIDINE DERIVATIVES PFIZER (US) 2023-06-22 US claimed
WO-2023077216-A1 HEAT SHOCK PROTEIN 90 (HSP90) INHIBITORS FOR TREATING FUNGAL INFECTIONS AND METHODS OF USE THEREOF BRIGHT ANGEL THERAPEUTICS INC. (CA) 2023-05-11 WO claimed
US-20220204484-A1 CHEMICAL INHIBITION OF THE E3 LIGASE SUBUNIT FBXO7 CONFERS NEUROPROTECTION AND ANTI-INFLAMMATORY ACTIVITY BY STABILIZING MITOCHONDRIA UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 2022-06-30 US claimed
US-11242339-B2 Chemical inhibition of the E3 ligase subunit FBXO7 confers neuroprotection and anti-inflammatory activity by stabilizing mitochondria University of Pittsburgh—of the Commonwealth System of Higher Education (US) 2022-02-08 US claimed
US-20210309659-A1 5,7-DIHYDRO-PYRROLO-PYRIDINE DERIVATIVES PFIZER (US) 2021-10-07 US claimed
US-20210198235-A1 DERIVATIVES OF PIPERLONGUMINE AND USES THEREOF AURANSA INC. 2021-07-01 US claimed
EP-3478679-B1 5,7-DIHYDRO-PYRROLO-PYRIDINE DERIVATIVES FOR TREATING NEUROLOGICAL AND NEURODEGENERATIVE DISEASES PFIZER (US) 2021-04-21 EP claimed
US-20110172203-A1 Substituted Imidazopyridinyl-Aminopyridine Compounds ARQULE, INC. (US) 2011-07-14 US claimed
WO-2011082270-A2 SUBSTITUTED IMIDAZOPYRIDINYL-AMINOPYRIDINE COMPOUNDS ARQULE. INC. (US) 2011-07-07 WO claimed
EP-1951725-B1 N-SULFAMOYL-N -BENZOPYRANPIPERIDINES AS INHBITORS OF CARBONIC ANHYDRASES ABBOTT PRODUCTS GMBH (DE) 2010-11-03 EP claimed
US-7547708-B2 N-sulfamoyl-N′-benzopyranpiperidine compounds and uses thereof SOLVAY PHARMACEUTICALS, INC. (DE) 2009-06-16 US claimed
EP-1951725-A1 N-SULFAMOYL-N -BENZOPYRANPIPERIDINES AS INHBITORS OF CARBONIC ANHYDRASES Solvay Pharmaceuticals GmbH (DE) 2008-08-06 EP claimed
US-20070117823-A1 N-sulfamoyl-N'-benzopyranpiperidine compounds and uses thereof SOLVAY PHARMACEUTICALSS GMBH (DE) 2007-05-24 US claimed
WO-2007054580-A1 N-SULFAMOYL-N’-BENZOPYRANPIPERIDINES AS INHBITORS OF CARBONIC ANHYDRASES SOLVAY PHARMACEUTICALS GMBH (DE) 2007-05-18 WO claimed
EP-0956286-B1 SYNTHESIS OF TERFENADINE AND DERIVATIVES SEPRACOR INC (US) 2003-04-02 EP claimed
EP-0093620-B1 FUNGICIDAL N-PHENYLCARBAMATES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-01-07 EP claimed
EP-0093620-A1 Fungicidal N-phenylcarbamates SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1983-11-09 EP claimed