Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.54 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.50 |
| ▸ | TUBB | P07437 | 1/20 | 0.50 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.50 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.50 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.50 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.50 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.50 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.50 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4999644 | 0.84 | POLB (0.70) | POLBMEN1KMT2AHTTNPC1 | |
| SCHEMBL30597986 | 0.83 | NPSR1 (0.58) | POLBMEN1KMT2ANPC1RAB9A | |
| SCHEMBL13777928 | 0.83 | NPSR1 (0.58) | POLBMEN1KMT2ANPC1RAB9A | |
| SCHEMBL29149452 | 0.81 | POLB (0.51) | POLBMEN1KMT2ASMN1; SMN2PARP1 | |
| SCHEMBL30434482 | 0.81 | POLB (0.55) | POLBALDH1A1MEN1KMT2AHTT | |
| SCHEMBL28103666 | 0.81 | POLB (0.55) | POLBALDH1A1MEN1KMT2AHTT | |
| SCHEMBL29149345 | 0.80 | POLB (0.46) | POLBMTNR1AMTNR1BMEN1KMT2A | |
| SCHEMBL29938626 | 0.80 | POLB (0.46) | POLBMTNR1AMTNR1BMEN1KMT2A | |
| SCHEMBL2222173 | 0.80 | POLB (0.63) | POLBMEN1KMT2ASMN1; SMN2PARP1 | |
| SCHEMBL2222163 | 0.80 | POLB (0.63) | POLBMEN1KMT2ASMN1; SMN2PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107556366-B | Compound having mutant isocitrate dehydrogenase inhibitory activity, process for producing the same, and use thereof | 上海海和药物研究开发股份有限公司 | 2025-02-07 | — | — | CN | disclosed |