Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STK3 | Q13188 | 16/20 | 0.66 |
| ▸ | STK4 | Q13043 | 14/20 | 0.66 |
| ▸ | LRRK2 | Q5S007 | 10/20 | 0.66 |
| ▸ | BRAF | P15056 | 1/20 | 0.56 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.56 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.47 |
| ▸ | CDC7 | O00311 | 2/20 | 0.47 |
| ▸ | CHUK | O15111 | 2/20 | 0.47 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.47 |
| ▸ | DYRK3 | O43781 | 2/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.47 |
| ▸ | RPS6KA5 | O75582 | 2/20 | 0.47 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.47 |
| ▸ | PRKCG | P05129 | 2/20 | 0.47 |
| ▸ | LCK | P06239 | 2/20 | 0.47 |
| ▸ | FYN | P06241 | 2/20 | 0.47 |
| ▸ | CDK1 | P06493 | 2/20 | 0.47 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.47 |
| ▸ | PHKG2 | P15735 | 2/20 | 0.47 |
| ▸ | PRKACA | P17612 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30295797 | 0.97 | STK3 (0.69) | STK3STK4LRRK2BRAFTNNI3K | |
| SCHEMBL30295832 | 0.91 | STK3 (0.66) | STK3STK4LRRK2BRAFTNNI3K | |
| SCHEMBL30295830 | 0.90 | STK3 (0.70) | STK3STK4LRRK2BRAFTNNI3K | |
| SCHEMBL31301686 | 0.90 | STK3 (0.69) | STK3STK4LRRK2BRAFTNNI3K | |
| SCHEMBL30295764 | 0.89 | STK3 (0.62) | STK3STK4LRRK2BRAFTNNI3K | |
| SCHEMBL31301818 | 0.88 | STK3 (0.62) | STK3STK4LRRK2BRAFTNNI3K | |
| SCHEMBL30295899 | 0.88 | STK3 (0.70) | STK3STK4LRRK2BRAFTNNI3K | |
| SCHEMBL31301726 | 0.85 | STK3 (0.72) | STK3STK4LRRK2BRAFTNNI3K | |
| SCHEMBL31301641 | 0.85 | STK3 (0.72) | STK3STK4LRRK2BRAFTNNI3K | |
| SCHEMBL30295782 | 0.84 | STK3 (0.65) | STK3STK4LRRK2BRAFTNNI3K |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250051337-A1 | INHIBITORS OF SERINE/THREONINE PROTEIN KINASE STK3 OR STK4 AND USES THEREOF | Sanford Burnham Prebys Medical Discovery Institute | 2025-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250051337-A1 | INHIBITORS OF SERINE/THREONINE PROTEIN KINASE STK3 OR STK4 AND USES THEREOF | STK3, STK4, STK36 | STK3 1/4885STK4 2/4885LRRK2 210/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.