Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 9/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.40 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19013504 | 0.88 | CHRM2 (0.44) | CHRM2CHRM4CHRM1CHRM3L3MBTL1 | |
| SCHEMBL18992345 | 0.86 | CHRM2 (0.43) | CHRM2CHRM4CHRM1CHRM3L3MBTL1 | |
| SCHEMBL29631844 | 0.86 | CHRM2 (0.43) | CHRM2CHRM4CHRM1CHRM3L3MBTL1 | |
| SCHEMBL30721518 | 0.81 | NQO2 (0.45) | CHRM2CHRM4CHRM1CHRM3NR1H2 | |
| SCHEMBL2003127 | 0.79 | CHRM2 (0.44) | CHRM2CHRM4CHRM1CHRM3L3MBTL1 | |
| SCHEMBL19013036 | 0.77 | CHRM2 (0.43) | CHRM2CHRM4CHRM1CHRM3L3MBTL1 | |
| SCHEMBL20226388 | 0.76 | CHRM2 (0.46) | CHRM2CHRM4CHRM1CHRM3L3MBTL1 | |
| SCHEMBL19164253 | 0.76 | CHRM2 (0.49) | CHRM2CHRM4CHRM1CHRM3L3MBTL1 | |
| SCHEMBL19013560 | 0.73 | NR1H2 (0.43) | CHRM2CHRM4CHRM1CHRM3L3MBTL1 | |
| SCHEMBL28817783 | 0.73 | NR1H2 (0.43) | CHRM2CHRM4CHRM1CHRM3NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024258789-A1 | MODULATORS OF CDK2 AND USES THEREOF | TRIANA BIOMEDICINES, INC. (US) | 2024-12-19 | — | — | WO | disclosed |